doxazosin has been researched along with Brain Infarction in 1 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted ambulatory BP monitoring three times (twice at baseline and after nighttime dosing of the alpha1-blocker doxazosin) in 98 elderly hypertensive patients in whom the presence of silent cerebral infarcts (SCI) was assessed by brain magnetic resonance imaging." | 5.11 | Morning blood pressure surge and hypertensive cerebrovascular disease: role of the alpha adrenergic sympathetic nervous system. ( Eguchi, K; Hoshide, S; Hoshide, Y; Ishikawa, J; Kario, K; Morinari, M; Pickering, TG; Shimada, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kario, K | 1 |
| Pickering, TG | 1 |
| Hoshide, S | 1 |
| Eguchi, K | 1 |
| Ishikawa, J | 1 |
| Morinari, M | 1 |
| Hoshide, Y | 1 |
| Shimada, K | 1 |
1 trial available for doxazosin and Brain Infarction
| Article | Year |
|---|---|
Morning blood pressure surge and hypertensive cerebrovascular disease: role of the alpha adrenergic sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Aged; Aging; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Br | 2004 |