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doxazosin and Angiogenesis, Pathologic

doxazosin has been researched along with Angiogenesis, Pathologic in 2 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Research Excerpts

ExcerptRelevanceReference
"Doxazosin is an α1 adrenergic receptor blocker that also exerts antitumor effects."1.40The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression. ( Dong, SM; Kim, BR; Kim, DY; Lee, SH; Park, MS; Rho, SB, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, MS1
Kim, BR1
Dong, SM1
Lee, SH1
Kim, DY1
Rho, SB1
Garrison, JB1
Shaw, YJ1
Chen, CS1
Kyprianou, N1

Other Studies

2 other studies available for doxazosin and Angiogenesis, Pathologic

ArticleYear
The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR-2/Akt/mTOR signaling and VEGF and HIF-1α expression.
    Oncotarget, 2014, Jul-15, Volume: 5, Issue:13

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Antihypertensive Agents; Blotting, Western; Cell L

2014
Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity.
    Cancer research, 2007, Dec-01, Volume: 67, Issue:23

    Topics: Adrenergic alpha-Antagonists; Animals; Apoptosis; Blotting, Western; Cell Adhesion; Cell Movement; C

2007