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doxazosin and Anesthesia

doxazosin has been researched along with Anesthesia in 6 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Pheochromocytoma is associated with intense physiologic effects of alpha- and beta-adrenergic stimulation from catecholamine secretion."1.33The perioperative management of a patient with complex single ventricle physiology and pheochromocytoma. ( McGowan, FX; Seefelder, C; Shamberger, RC; Sparks, JW, 2005)
"Doxazosin was more potent than terazosin, in that there was a significant reduction in hypogastric nerve activity after 20 min (0."1.29A comparison of the effects of doxazosin and terazosin on the spontaneous sympathetic drive to the bladder and related organs in anaesthetized cats. ( Ramage, AG; Wyllie, MG, 1995)
"In previously untreated rats, pretreatment with enalaprilat shifted the dose-response curve for the hypotensive effect of doxazosin to the left, indicating synergism."1.28A study of the interaction between the hypotensive actions of doxazosin and enalaprilat in anaesthetized rats. ( Marwood, JF; Stokes, GS; Tierney, G, 1992)
"Doxazosin 1 mg kg was found to be a potent alpha 1-adrenoceptor antagonist."1.28Investigations into interactions between doxazosin and enalaprilat at alpha 1-adrenoceptors in anaesthetized rats. ( Marwood, J; Stokes, G; Tierney, G, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhou, J1
Luan, GD1
Ren, LM1
Wu, ZG1
Wang, X1
Zhao, Y1
Sparks, JW1
Seefelder, C1
Shamberger, RC1
McGowan, FX1
Ramage, AG1
Wyllie, MG1
Marwood, JF1
Tierney, G2
Stokes, GS1
Marwood, J1
Stokes, G1
Alabaster, VA1
Davey, MJ1

Other Studies

6 other studies available for doxazosin and Anesthesia

ArticleYear
Pharmacologic characteristics of bladder micturition function in anesthetized mice.
    Comparative medicine, 2010, Volume: 60, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agoni

2010
The perioperative management of a patient with complex single ventricle physiology and pheochromocytoma.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Anesthesia; Blood Pressure; Double Out

2005
A comparison of the effects of doxazosin and terazosin on the spontaneous sympathetic drive to the bladder and related organs in anaesthetized cats.
    European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pr

1995
A study of the interaction between the hypotensive actions of doxazosin and enalaprilat in anaesthetized rats.
    Journal of hypertension, 1992, Volume: 10, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Desoxycorticosterone; Disease Models, Animal; Dose-Res

1992
Investigations into interactions between doxazosin and enalaprilat at alpha 1-adrenoceptors in anaesthetized rats.
    Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Angiotensin II; Animals; Desoxycorticosterone; Doxazosin;

1991
The alpha 1-adrenoceptor antagonist profile of doxazosin: preclinical pharmacology.
    British journal of clinical pharmacology, 1986, Volume: 21 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Angiotensin II; Animals; Antihypertensive Agents; Cats; Do

1986