Page last updated: 2024-10-26

doxazosin and Allergic Rhinitis

doxazosin has been researched along with Allergic Rhinitis in 1 studies

Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.

Research Excerpts

ExcerptRelevanceReference
"We examined the paradoxical hypothesis that the alpha-receptor inverse agonist doxazosin might produce beneficial effects in allergic rhinitis."9.22Effects of the inverse alpha-agonist doxazosin in allergic rhinitis. ( Lipworth, BJ; Manoharan, A; Morrison, AE, 2016)
"We examined the paradoxical hypothesis that the alpha-receptor inverse agonist doxazosin might produce beneficial effects in allergic rhinitis."5.22Effects of the inverse alpha-agonist doxazosin in allergic rhinitis. ( Lipworth, BJ; Manoharan, A; Morrison, AE, 2016)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manoharan, A1
Morrison, AE1
Lipworth, BJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Proof of Concept Study in Allergic Rhinitis, to Evaluate the Differential Effects Between Single and Chronic Dosing of Doxazosin on Nasal Airway Calibre[NCT01946035]Phase 417 participants (Actual)Interventional2013-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for doxazosin and Allergic Rhinitis

ArticleYear
Effects of the inverse alpha-agonist doxazosin in allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2016, Volume: 46, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Biomarkers; Doxazosin; Female; Humans; Male; Nasal Provocat

2016