doxazosin has been researched along with Alcohol Drinking in 6 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxazosin decreases voluntary alcohol consumption by male alcohol-preferring (P) rats, supporting a role for the noradrenergic system in alcohol drinking in P rats and suggesting that doxazosin could potentially be an effective once-daily pharmacotherapeutic agent for the treatment of alcohol use disorders." | 7.79 | The α1-adrenergic receptor antagonist, doxazosin, reduces alcohol drinking in alcohol-preferring (P) Rats. ( Beckwith, LE; Kincaid, CL; O'Neil, ML; Rasmussen, DD, 2013) |
| "Doxazosin decreases voluntary alcohol consumption by male alcohol-preferring (P) rats, supporting a role for the noradrenergic system in alcohol drinking in P rats and suggesting that doxazosin could potentially be an effective once-daily pharmacotherapeutic agent for the treatment of alcohol use disorders." | 3.79 | The α1-adrenergic receptor antagonist, doxazosin, reduces alcohol drinking in alcohol-preferring (P) Rats. ( Beckwith, LE; Kincaid, CL; O'Neil, ML; Rasmussen, DD, 2013) |
| "The comorbidity between alcohol use disorder and post-traumatic stress disorder represents a serious health care burden with few effective treatment options." | 1.56 | Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress. ( Becker, HC; Carper, BA; Lopez, MF; Nolen, TL; Reasons, SE; Williams, RL, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, MF | 1 |
| Reasons, SE | 1 |
| Carper, BA | 1 |
| Nolen, TL | 1 |
| Williams, RL | 1 |
| Becker, HC | 1 |
| Haass-Koffler, CL | 1 |
| Goodyear, K | 1 |
| Zywiak, WH | 1 |
| Magill, M | 1 |
| Eltinge, SE | 1 |
| Wallace, PM | 1 |
| Long, VM | 1 |
| Jayaram-Lindström, N | 1 |
| Swift, RM | 1 |
| Kenna, GA | 2 |
| Leggio, L | 2 |
| Funk, D | 1 |
| Coen, K | 1 |
| Tamadon, S | 1 |
| Li, Z | 1 |
| Loughlin, A | 1 |
| Lê, AD | 1 |
| O'Neil, ML | 1 |
| Beckwith, LE | 1 |
| Kincaid, CL | 1 |
| Rasmussen, DD | 1 |
| Diener, HC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Focus on Alpha-1 Blockade as a Novel Pharmacological Treatment for AUD[NCT04135846] | Phase 2 | 184 participants (Anticipated) | Interventional | 2019-12-19 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for doxazosin and Alcohol Drinking
| Article | Year |
|---|---|
Higher pretreatment blood pressure is associated with greater alcohol drinking reduction in alcohol-dependent individuals treated with doxazosin.
Topics: Adult; Alcohol Drinking; Alcoholism; Blood Pressure; Double-Blind Method; Doxazosin; Female; Humans; | 2017 |
5 other studies available for doxazosin and Alcohol Drinking
| Article | Year |
|---|---|
Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Topics: Alcohol Drinking; Alcoholism; Animals; Doxazosin; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; S | 2020 |
Effects of prazosin and doxazosin on yohimbine-induced reinstatement of alcohol seeking in rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Alcohol Drinking; Animals; Br | 2016 |
The α1-adrenergic receptor antagonist, doxazosin, reduces alcohol drinking in alcohol-preferring (P) Rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alcohol Drinking; Animals; Choice Behavior; Disease Models, | 2013 |
Commentary: Doxazosin for alcoholism.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alcohol Drinking; Alcoholism; Animals; Disease Models, Anim | 2013 |
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic | 2003 |