doxazosin has been researched along with Alcohol Abuse in 5 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD) are two of the most common mental health disorders affecting civilians as well as military populations." | 2.87 | Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans. ( Augur, I; Back, SE; Brady, KT; Flanagan, JC; Hancock, AK; Henschel, A; Jones, JL; Joseph, JE; Keane, TM; Litz, BT; Mintz, J; Peterson, AL; Roache, JD; Shirley, DW; Wachen, JS; Young-McCaughan, S, 2018) |
| "The comorbidity between alcohol use disorder and post-traumatic stress disorder represents a serious health care burden with few effective treatment options." | 1.56 | Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress. ( Becker, HC; Carper, BA; Lopez, MF; Nolen, TL; Reasons, SE; Williams, RL, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, MF | 1 |
| Reasons, SE | 1 |
| Carper, BA | 1 |
| Nolen, TL | 1 |
| Williams, RL | 1 |
| Becker, HC | 1 |
| Haass-Koffler, CL | 2 |
| Goodyear, K | 1 |
| Zywiak, WH | 2 |
| Magill, M | 1 |
| Eltinge, SE | 1 |
| Wallace, PM | 1 |
| Long, VM | 1 |
| Jayaram-Lindström, N | 1 |
| Swift, RM | 2 |
| Kenna, GA | 3 |
| Leggio, L | 3 |
| Back, SE | 1 |
| Flanagan, JC | 1 |
| Jones, JL | 1 |
| Augur, I | 1 |
| Peterson, AL | 1 |
| Young-McCaughan, S | 1 |
| Shirley, DW | 1 |
| Henschel, A | 1 |
| Joseph, JE | 1 |
| Litz, BT | 1 |
| Hancock, AK | 1 |
| Roache, JD | 1 |
| Mintz, J | 1 |
| Wachen, JS | 1 |
| Keane, TM | 1 |
| Brady, KT | 1 |
| Edwards, SM | 1 |
| Brickley, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Focus on Alpha-1 Blockade as a Novel Pharmacological Treatment for AUD[NCT04135846] | Phase 2 | 184 participants (Anticipated) | Interventional | 2019-12-19 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for doxazosin and Alcohol Abuse
| Article | Year |
|---|---|
Higher pretreatment blood pressure is associated with greater alcohol drinking reduction in alcohol-dependent individuals treated with doxazosin.
Topics: Adult; Alcohol Drinking; Alcoholism; Blood Pressure; Double-Blind Method; Doxazosin; Female; Humans; | 2017 |
Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alcoholism; Brain; Double-Blind Method; Doxazosin; Function | 2018 |
Role of the α1 blocker doxazosin in alcoholism: a proof-of-concept randomized controlled trial.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Alcoholism; Double-Blind Method; Doxazosin; Female; | 2016 |
2 other studies available for doxazosin and Alcohol Abuse
| Article | Year |
|---|---|
Evaluation of the effect of doxasozin and zonisamide on voluntary ethanol intake in mice that experienced chronic intermittent ethanol exposure and stress.
Topics: Alcohol Drinking; Alcoholism; Animals; Doxazosin; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; S | 2020 |
Commentary: Doxazosin for alcoholism.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alcohol Drinking; Alcoholism; Animals; Disease Models, Anim | 2013 |