doxazosin has been researched along with Acute Post-Traumatic Stress Disorder in 3 studies
Doxazosin: A prazosin-related compound that is a selective alpha-1-adrenergic blocker.
doxazosin : A member of the class of quinazolines that is quinazoline substituted by an amino group at position 4, methoxy groups at positions 6 and 7 and a piperazin-1-yl group at position 2 which in turn is substituted by a 2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl group at position 4. An antihypertensive agent, it is used in the treatment of high blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD) are two of the most common mental health disorders affecting civilians as well as military populations." | 2.87 | Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans. ( Augur, I; Back, SE; Brady, KT; Flanagan, JC; Hancock, AK; Henschel, A; Jones, JL; Joseph, JE; Keane, TM; Litz, BT; Mintz, J; Peterson, AL; Roache, JD; Shirley, DW; Wachen, JS; Young-McCaughan, S, 2018) |
| "Doxazosin XL treatment was associated with a nonsignificant treatment × time reduction in ratings on the CAPS hyperarousal subscale (P < ." | 2.82 | Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial. ( De La Garza, R; Haile, CN; Holst, M; Newton, TF; Raskind, MA; Rodgman, C; Thompson-Lake, D; Verrico, CD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Back, SE | 1 |
| Flanagan, JC | 1 |
| Jones, JL | 1 |
| Augur, I | 1 |
| Peterson, AL | 1 |
| Young-McCaughan, S | 1 |
| Shirley, DW | 1 |
| Henschel, A | 1 |
| Joseph, JE | 1 |
| Litz, BT | 1 |
| Hancock, AK | 1 |
| Roache, JD | 1 |
| Mintz, J | 1 |
| Wachen, JS | 1 |
| Keane, TM | 1 |
| Brady, KT | 1 |
| Rodgman, C | 1 |
| Verrico, CD | 1 |
| Holst, M | 1 |
| Thompson-Lake, D | 1 |
| Haile, CN | 1 |
| De La Garza, R | 1 |
| Raskind, MA | 1 |
| Newton, TF | 1 |
| De Jong, J | 1 |
| Wauben, P | 1 |
| Huijbrechts, I | 1 |
| Oolders, H | 1 |
| Haffmans, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Label 8-Week Study of Prazosin Use in Adults With Anxiety Disorders[NCT03894345] | Phase 1 | 20 participants (Anticipated) | Interventional | 2019-05-24 | Suspended (stopped due to COVID-19) | ||
| DOXAZOSIN AS A TREATMENT FOR POST TRAUMATIC STRESS SYNDROME[NCT02308202] | Phase 1 | 30 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD[NCT01959022] | Phase 4 | 15 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| A Randomized, Double-Blind, Placebo-Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in Post-Traumatic Stress[NCT03339258] | Phase 2 | 80 participants (Anticipated) | Interventional | 2018-04-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for doxazosin and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Doxazosin for the treatment of co-occurring PTSD and alcohol use disorder: Design and methodology of a randomized controlled trial in military veterans.
Topics: Adrenergic alpha-1 Receptor Antagonists; Alcoholism; Brain; Double-Blind Method; Doxazosin; Function | 2018 |
Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial.
Topics: Adult; Child; Delayed-Action Preparations; Double-Blind Method; Doxazosin; Humans; Metabolic Clearan | 2016 |
Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial.
Topics: Adult; Child; Delayed-Action Preparations; Double-Blind Method; Doxazosin; Humans; Metabolic Clearan | 2016 |
Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial.
Topics: Adult; Child; Delayed-Action Preparations; Double-Blind Method; Doxazosin; Humans; Metabolic Clearan | 2016 |
Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial.
Topics: Adult; Child; Delayed-Action Preparations; Double-Blind Method; Doxazosin; Humans; Metabolic Clearan | 2016 |
1 other study available for doxazosin and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Doxazosin treatment for posttraumatic stress disorder.
Topics: Adrenergic alpha-Antagonists; Adult; Delayed-Action Preparations; Doxazosin; Female; Humans; Male; P | 2010 |
Doxazosin treatment for posttraumatic stress disorder.
Topics: Adrenergic alpha-Antagonists; Adult; Delayed-Action Preparations; Doxazosin; Female; Humans; Male; P | 2010 |
Doxazosin treatment for posttraumatic stress disorder.
Topics: Adrenergic alpha-Antagonists; Adult; Delayed-Action Preparations; Doxazosin; Female; Humans; Male; P | 2010 |
Doxazosin treatment for posttraumatic stress disorder.
Topics: Adrenergic alpha-Antagonists; Adult; Delayed-Action Preparations; Doxazosin; Female; Humans; Male; P | 2010 |