doxapram has been researched along with Respiration Disorders in 7 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Respiration Disorders: Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sebel, PS | 1 |
| Kershaw, EJ | 1 |
| Rao, WS | 1 |
| Gautier, H | 1 |
| Bonora, M | 1 |
| Grote, B | 1 |
| Kugler, J | 1 |
| Gutzeit, M | 1 |
| Doenicke, A | 1 |
| Haddad, GG | 1 |
| Mazza, NM | 1 |
| Defendini, R | 1 |
| Blanc, WA | 1 |
| Driscoll, JM | 1 |
| Epstein, MA | 1 |
| Epstein, RA | 1 |
| Mellins, RB | 1 |
| Bairam, A | 1 |
| Boutroy, MJ | 1 |
| Vert, P | 1 |
| Haake, RE | 1 |
| Saxon, LA | 1 |
| Bander, SJ | 1 |
| Haake, RJ | 1 |
| Olsen, KH | 1 |
| Melsen, NC | 1 |
| Thorshauge, H | 1 |
| Christensen, JH | 1 |
1 review available for doxapram and Respiration Disorders
| Article | Year |
|---|---|
[A respiratory stimulant, doxapram, and its use in pediatrics].
Topics: Child; Doxapram; Drug Evaluation; Humans; Infant, Newborn; Respiration Disorders; Respiratory Center | 1992 |
3 trials available for doxapram and Respiration Disorders
| Article | Year |
|---|---|
Effects of doxapram on postoperative pulmonary complications following thoracotomy.
Topics: Carbon Dioxide; Doxapram; Female; Humans; Hydrogen-Ion Concentration; Lung; Male; Oxygen; Partial Pr | 1980 |
[The influence of doxapram in human on the respiratory depression by fentanyl (author's transl)].
Topics: Depression, Chemical; Doxapram; Drug Evaluation; Fentanyl; Humans; Respiration Disorders | 1978 |
[The effect of doxapram after thoracotomy].
Topics: Clinical Trials as Topic; Double-Blind Method; Doxapram; Humans; Pneumonectomy; Postoperative Compli | 1986 |
3 other studies available for doxapram and Respiration Disorders
| Article | Year |
|---|---|
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; D | 1980 |
Congenital failure of automatic control of ventilation, gastrointestinal motility and heart rate.
Topics: Doxapram; Female; Heart Rate; Humans; Hypoventilation; Infant, Newborn; Megacolon; Respiration; Resp | 1978 |
Depressed central respiratory drive causing weaning failure. Its reversal with doxapram.
Topics: Doxapram; Female; Humans; Middle Aged; Respiration Disorders; Ventilator Weaning | 1989 |