doxapram has been researched along with Pain, Postoperative in 4 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxapram reversed the respiratory depression but did not alter analgesia." | 2.65 | Antagonists of morphine-induced respiratory depression. A study in postoperative patients. ( Gairola, RL; Gupta, PK; Pandley, K, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, D | 1 |
| Chai, W | 1 |
| Sun, X | 1 |
| Yao, L | 1 |
| Gairola, RL | 1 |
| Gupta, PK | 1 |
| Pandley, K | 1 |
| Cundy, JM | 1 |
| Clyburn, PA | 1 |
| Rosen, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant[NCT02819089] | 100 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | |||
| Comparison of Two Different Anesthetic Techniques on Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position: A Prospective Randomized Clinical Trial[NCT03572517] | 65 participants (Actual) | Interventional | 2017-09-01 | Completed | |||
| The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty: A Randomized, Controlled Trial[NCT05601674] | 76 participants (Actual) | Interventional | 2022-11-04 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for doxapram and Pain, Postoperative
| Article | Year |
|---|---|
Antagonists of morphine-induced respiratory depression. A study in postoperative patients.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Doxapram; Humans; Levallorphan; Middle Aged; M | 1980 |
Patient-controlled analgesia with a mixture of pethidine and doxapram hydrochloride. A comparison of the incidence of respiratory dysrhythmias with pethidine alone.
Topics: Adult; Aged; Apnea; Carbon Dioxide; Doxapram; Drug Therapy, Combination; Female; Humans; Male; Meper | 1988 |
2 other studies available for doxapram and Pain, Postoperative
| Article | Year |
|---|---|
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation in adults: risk factors in 2,000 patients.
Topics: Adolescent; Adult; Aged; Analgesics; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Postoperative analgesia using continuous infusion of papaveretum.
Topics: Aminophylline; Doxapram; Humans; Infusions, Parenteral; Pain, Postoperative | 1979 |