doxapram has been researched along with Muscle Contraction in 4 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
McGuire, M | 1 |
Carey, MF | 1 |
O'Connor, JJ | 1 |
Orlowski, M | 1 |
Pollard, BJ | 2 |
Randall, NP | 1 |
Pleuvry, BJ | 1 |
Kuga, T | 1 |
Naito, J | 1 |
1 trial available for doxapram and Muscle Contraction
Article | Year |
---|---|
Effect of doxapram on neostigmine evoked antagonism of vecuronium neuromuscular block.
Topics: Adult; Anesthesia, General; Depression, Chemical; Double-Blind Method; Doxapram; Drug Interactions; | 1992 |
3 other studies available for doxapram and Muscle Contraction
Article | Year |
---|---|
Almitrine and doxapram decrease fatigue and increase subsequent recovery in isolated rat diaphragm.
Topics: Almitrine; Animals; Diaphragm; Doxapram; Electric Stimulation; In Vitro Techniques; Isometric Contra | 1997 |
Doxapram and the neuromuscular junction.
Topics: Acetylcholinesterase; Animals; Diaphragm; Dose-Response Relationship, Drug; Doxapram; Male; Muscle C | 1989 |
[Pharmacological action of 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolinone hydrochloride (doxapram). 2. Peripheral action].
Topics: Animals; Autonomic Nervous System; Diaphragm; Doxapram; Female; Gastrointestinal Motility; Guinea Pi | 1974 |