doxapram has been researched along with Liver Diseases in 1 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the first case of acute hepatic necrosis, which we believe to have been caused by the administration of the respiratory stimulant, doxapram hydrochloride (Dopram)." | 7.67 | Hepatic necrosis with doxapram hydrochloride. ( Ashton, RJ; Fancourt, GJ; Talbot, IC; Wales, JM, 1985) |
| "We report the first case of acute hepatic necrosis, which we believe to have been caused by the administration of the respiratory stimulant, doxapram hydrochloride (Dopram)." | 3.67 | Hepatic necrosis with doxapram hydrochloride. ( Ashton, RJ; Fancourt, GJ; Talbot, IC; Wales, JM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fancourt, GJ | 1 |
| Ashton, RJ | 1 |
| Talbot, IC | 1 |
| Wales, JM | 1 |
1 other study available for doxapram and Liver Diseases
| Article | Year |
|---|---|
Hepatic necrosis with doxapram hydrochloride.
Topics: Aged; Chemical and Drug Induced Liver Injury; Doxapram; Humans; Liver Diseases; Male; Necrosis | 1985 |