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doxapram and Leukomalacia, Periventricular

doxapram has been researched along with Leukomalacia, Periventricular in 1 studies

Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Leukomalacia, Periventricular: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

Research Excerpts

ExcerptRelevanceReference
"of doxapram."1.31Doxapram accentuates white matter injury in neonatal rats following bilateral carotid artery occlusion. ( Hasegawa, K; Nagai, H; Naito, T; Ochiai, R; Sawada, T; Uehara, H; Yoshioka, H, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Uehara, H1
Yoshioka, H1
Nagai, H1
Ochiai, R1
Naito, T1
Hasegawa, K1
Sawada, T1

Other Studies

1 other study available for doxapram and Leukomalacia, Periventricular

ArticleYear
Doxapram accentuates white matter injury in neonatal rats following bilateral carotid artery occlusion.
    Neuroscience letters, 2000, Mar-10, Volume: 281, Issue:2-3

    Topics: Animals; Animals, Newborn; Arterial Occlusive Diseases; Brain; Carotid Arteries; Doxapram; Humans; I

2000