doxapram has been researched along with Infantile Respiratory Distress Syndrome in 3 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Doxapram-induced hypokalemia may be due to an inappropriate increase in aldosterone levels." | 3.88 | Blood potassium and urine aldosterone after doxapram therapy for preterm infants. ( Itani, Y; Shibasaki, J; Shimokaze, T; Toyoshima, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shimokaze, T | 1 |
| Toyoshima, K | 1 |
| Shibasaki, J | 1 |
| Itani, Y | 1 |
| Greenough, A | 1 |
| Prendergast, M | 1 |
| Eyal, FG | 1 |
| Sagi, EF | 1 |
| Alpan, G | 1 |
| Glick, B | 1 |
| Arad, I | 1 |
1 review available for doxapram and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Difficult extubation in low birthweight infants.
Topics: Adrenal Cortex Hormones; Bronchopulmonary Dysplasia; Decision Making; Dexamethasone; Doxapram; Gluco | 2008 |
1 trial available for doxapram and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Aminophylline versus doxapram in weaning premature infants from mechanical ventilation: preliminary report.
Topics: Aminophylline; Double-Blind Method; Doxapram; Humans; Infant, Newborn; Infant, Premature; Positive-P | 1985 |
1 other study available for doxapram and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Blood potassium and urine aldosterone after doxapram therapy for preterm infants.
Topics: Aldosterone; Cohort Studies; Creatinine; Dose-Response Relationship, Drug; Doxapram; Drug Administra | 2018 |