doxapram has been researched along with Hypothermia, Accidental in 4 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ventilatory responses, blood gases and acid-base status to intravenous injections of KCN and doxapram hydrochloride were studied in anesthetized dogs during normothermia and at two levels of hypothermia." | 7.65 | Effects of cyanide and doxapram during hypothermia. ( Ruiz, AV, 1975) |
| "The ventilatory responses, blood gases and acid-base status to intravenous injections of KCN and doxapram hydrochloride were studied in anesthetized dogs during normothermia and at two levels of hypothermia." | 3.65 | Effects of cyanide and doxapram during hypothermia. ( Ruiz, AV, 1975) |
| "When doxapram was given intraperitoneally 60 min." | 1.28 | Interaction of doxapram and pentobarbital in mice. ( Ishikawa, M; Ozaki, M; Sasaki, K; Suzuki, I; Takayanagi, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ruiz, AV | 1 |
| Abdallah, AH | 1 |
| Roby, DM | 1 |
| Ishikawa, M | 1 |
| Suzuki, I | 1 |
| Ozaki, M | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
4 other studies available for doxapram and Hypothermia, Accidental
| Article | Year |
|---|---|
Effects of cyanide and doxapram during hypothermia.
Topics: Animals; Arteries; Carbon Dioxide; Chemoreceptor Cells; Cyanides; Dogs; Doxapram; Female; Hydrogen-I | 1975 |
Antagonism of depressant activity of ethanol by DH-524; a comparative study with Bemegride, Doxapram and d-amphetamine.
Topics: Amphetamine; Animals; Bemegride; Depression, Chemical; Doxapram; Ethanol; Humans; Hypothermia; Imida | 1975 |
Perioperative shivering.
Topics: Anesthesia; Body Temperature Regulation; Doxapram; Humans; Hypothermia; Intraoperative Complications | 1991 |
Interaction of doxapram and pentobarbital in mice.
Topics: Animals; Blood Proteins; Brain; Cytochrome P-450 Enzyme System; Doxapram; Drug Interactions; Guinea | 1991 |