doxapram has been researched along with Hyperventilation in 4 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Neither the cognitive intervention nor doxapram-induced hyperventilation produced significant changes in V(t) irregularity." | 5.09 | Persistent respiratory irregularity in patients with panic disorder. ( Abelson, JL; Curtis, GC; Nesse, RM; Weg, JG, 2001) |
| " Hyperventilation induced by 30 minutes of exercise, placement in a 39 degrees C water bath, or intravenous doxapram increased venous blood pH in dog 1 and control dogs, but transient hemoglobinemia, hemoglobinuria, and severe bilirubinuria occurred only in the studied patient." | 3.67 | Inherited phosphofructokinase deficiency in dogs with hyperventilation-induced hemolysis: increased in vitro and in vivo alkaline fragility of erythrocytes. ( Beutler, E; Chiapella, A; Giger, U; Harvey, JW; McNulty, PK; Yamaguchi, RA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abelson, JL | 2 |
| Khan, S | 1 |
| Lyubkin, M | 1 |
| Giardino, N | 1 |
| Busch, MA | 1 |
| Bisgard, GE | 1 |
| Mesina, JE | 1 |
| Forster, HV | 1 |
| Weg, JG | 1 |
| Nesse, RM | 1 |
| Curtis, GC | 1 |
| Giger, U | 1 |
| Harvey, JW | 1 |
| Yamaguchi, RA | 1 |
| McNulty, PK | 1 |
| Chiapella, A | 1 |
| Beutler, E | 1 |
2 trials available for doxapram and Hyperventilation
| Article | Year |
|---|---|
Respiratory irregularity and stress hormones in panic disorder: exploring potential linkages.
Topics: Adrenocorticotropic Hormone; Arousal; Attention; Central Nervous System Stimulants; Cues; Doxapram; | 2008 |
Persistent respiratory irregularity in patients with panic disorder.
Topics: Adult; Analysis of Variance; Cognitive Behavioral Therapy; Doxapram; Female; Humans; Hyperventilatio | 2001 |
2 other studies available for doxapram and Hyperventilation
| Article | Year |
|---|---|
The effects of unilateral carotid body excision on ventilatory control in goats.
Topics: Acclimatization; Animals; Carotid Body; Chemoreceptor Cells; Dopamine; Doxapram; Female; Goats; Hype | 1983 |
Inherited phosphofructokinase deficiency in dogs with hyperventilation-induced hemolysis: increased in vitro and in vivo alkaline fragility of erythrocytes.
Topics: Anemia, Hemolytic; Animals; Dogs; Doxapram; Erythrocytes; Hydrogen-Ion Concentration; Hyperventilati | 1985 |