doxapram has been researched along with Disease, Pulmonary in 5 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the benefits and harms of doxapram administration on the incidence of apnea and other short-term and longer-term clinical outcomes in preterm infants." | 9.41 | Doxapram for the prevention and treatment of apnea in preterm infants. ( Avdic, E; Bruschettini, M; Evans, S; Fiander, M; Pessano, S; Soll, R, 2023) |
| "To evaluate the benefits and harms of doxapram administration on the incidence of apnea and other short-term and longer-term clinical outcomes in preterm infants." | 5.41 | Doxapram for the prevention and treatment of apnea in preterm infants. ( Avdic, E; Bruschettini, M; Evans, S; Fiander, M; Pessano, S; Soll, R, 2023) |
| "In a double-blind study patients given a single dose of doxapram 1-5-2-0 mg/kg combined with morphine postoperatively had a significantly lower incidence of reflex postoperative cough and expectoration of purulent sputum than patients given morphine alone." | 5.04 | Role of doxapram in reducing pulmonary complications after major surgery. ( Dundee, JW; Gawley, TH; Gupta, PK; Jones, CJ, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evans, S | 1 |
| Avdic, E | 1 |
| Pessano, S | 1 |
| Fiander, M | 1 |
| Soll, R | 1 |
| Bruschettini, M | 1 |
| Drummond, GB | 1 |
| Park, GR | 1 |
| Steele, RJ | 1 |
| Walker, WS | 1 |
| Irvine, MK | 1 |
| Lee, D | 1 |
| Taylor, TV | 1 |
| Gawley, TH | 1 |
| Dundee, JW | 1 |
| Gupta, PK | 1 |
| Jones, CJ | 1 |
| Andersen, R | 1 |
| Krohg, K | 1 |
1 review available for doxapram and Disease, Pulmonary
| Article | Year |
|---|---|
Doxapram for the prevention and treatment of apnea in preterm infants.
Topics: Aminophylline; Apnea; Caffeine; Doxapram; Humans; Infant, Newborn; Infant, Premature; Lung Diseases | 2023 |
3 trials available for doxapram and Disease, Pulmonary
| Article | Year |
|---|---|
Doxapram and postoperative chest complications.
Topics: Abdomen; Clinical Trials as Topic; Cough; Double-Blind Method; Doxapram; Female; Humans; Lung Diseas | 1983 |
The use of doxapram in the prevention of postoperative pulmonary complications.
Topics: Clinical Trials as Topic; Doxapram; Female; Humans; Lung Diseases; Male; Postoperative Complications | 1982 |
Role of doxapram in reducing pulmonary complications after major surgery.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cough; Doxapram; Female; Humans; Lung Diseases; Male; M | 1976 |
1 other study available for doxapram and Disease, Pulmonary
| Article | Year |
|---|---|
Prevention of postoperative pulmonary complications. Intravenous analgesia combined with doxapram.
Topics: Doxapram; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Lung | 1976 |