Page last updated: 2024-10-26

doxapram and Diaphragmatic Paralysis

doxapram has been researched along with Diaphragmatic Paralysis in 1 studies

Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yoshida, T1
Uchiyama, A1
Matsuura, N1
Mashimo, T1
Fujino, Y1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Neuromuscular Blocking Agents on End Expiratory Lung Volume During Moderate-severe ARDS[NCT04996394]15 participants (Actual)Observational2019-12-12Completed
Airway Occlusion Measured During Non-invasive Ventilation to Assess Respiratory Effort[NCT05576246]12 participants (Anticipated)Observational2022-10-30Not yet recruiting
Driving Pressure Variation During Proportional Assisted Ventilation: Comparison Between NAVA and PSV[NCT03719365]20 participants (Anticipated)Interventional2018-11-01Recruiting
PRessure suppOrT vEntilation + Sigh in aCuTe hypoxemIc respiratOry Failure patieNts (PROTECTION): a Pilot Randomized Controlled Trial[NCT03201263]258 participants (Actual)Interventional2017-12-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for doxapram and Diaphragmatic Paralysis

ArticleYear
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013
The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury.
    Critical care medicine, 2013, Volume: 41, Issue:2

    Topics: Acute Lung Injury; Acute-Phase Proteins; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Flu

2013