doxapram has been researched along with Coma in 8 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Excerpt | Relevance | Reference |
---|---|---|
"A specific arousal therapy with NAGD (Naloxone, Activated Charcoal, Glucagon, Doxapram) is outlined for victims of drug overdose in comatose and semi-comatose states." | 3.66 | NAGD regimen for the coma of drug-related overdose. ( Decker, WJ; Gay, GR; Inaba, DS; Rappolt, RT, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (75.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (12.50) | 29.6817 |
2010's | 1 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Richards, JR | 1 |
Davis, MT | 1 |
Curry, MR | 1 |
Tsushima, JH | 1 |
McKinney, HE | 1 |
Rappolt, RT | 2 |
Gay, GR | 2 |
Decker, WJ | 1 |
Inaba, DS | 1 |
Inaba, D | 1 |
Miyamoto, M | 1 |
Miyamoto, T | 1 |
Hirata, K | 1 |
Ohresser, P | 1 |
Leonardelli, M | 1 |
Lareng, L | 1 |
Vaysse, C | 1 |
Cathala, B | 1 |
Plaut, MR | 1 |
Gifford, RR | 1 |
Jacobsen, PM | 1 |
Riordan, JF | 1 |
Sillett, RW | 1 |
McNicol, MW | 1 |
1 review available for doxapram and Coma
Article | Year |
---|---|
[Hypercapnic coma(CO2 narcosis)].
Topics: Central Nervous System Stimulants; Coma; Diagnosis, Differential; Doxapram; Humans; Hypercapnia; Oxy | 2000 |
7 other studies available for doxapram and Coma
Article | Year |
---|---|
Doxapram reversal of suspected gamma-hydroxybutyrate-induced coma.
Topics: Adjuvants, Anesthesia; Administration, Intravenous; Aged; Central Nervous System Stimulants; Coma; D | 2017 |
NAGD regimen for the coma of drug-related overdose.
Topics: Charcoal; Coma; Doxapram; Drug Therapy, Combination; Glucagon; Humans; Injections, Intravenous; Nalo | 1980 |
NAGD regime [naloxone (Narcan), activated charcoal, glucagon, doxapram (Dopram)] for the coma of drug-related overdoses.
Topics: Charcoal; Coma; Doxapram; Drug Administration Schedule; Glucagon; Humans; Naloxone; Poisoning | 1980 |
[Results using a respiratory analeptic: Dopram in resuscitation].
Topics: Adult; Aged; Central Nervous System Stimulants; Coma; Doxapram; Female; Humans; Injections, Intraven | 1969 |
[Use of doxapram hydrochloride in the treatment of drug toxic comas].
Topics: Adult; Central Nervous System Stimulants; Coma; Doxapram; Female; Humans; Male; Middle Aged; Morphol | 1971 |
Recovery from central respiratory failure and administration of doxapram to a patient with a brainstem lesion.
Topics: Apnea; Brain Stem; Cerebrovascular Disorders; Coma; Doxapram; Female; Humans; Middle Aged; Quadriple | 1973 |
Response to a respiratory stimulant (doxapram) in severe respiratory failure.
Topics: Aged; Blood; Bronchitis; Carbon Dioxide; Chronic Disease; Coma; Doxapram; Female; Humans; Hydrogen-I | 1974 |