Page last updated: 2024-10-26

doxapram and Canine Diseases

doxapram has been researched along with Canine Diseases in 6 studies

Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Research Excerpts

ExcerptRelevanceReference
"Dogs with laryngeal paralysis may suffer extreme glottic constriction with vigorous respirations, and may require intubation during examination."1.32Effects of doxapram HCl on laryngeal function of normal dogs and dogs with naturally occurring laryngeal paralysis. ( Harvey, RC; Jackson, AM; Tobias, KM, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Radkey, DI1
Hardie, RJ1
Smith, LJ1
Manens, J1
Bolognin, M1
Bernaerts, F1
Diez, M1
Kirschvink, N1
Clercx, C1
Tobias, KM1
Jackson, AM1
Harvey, RC1
Short, CE1
Alsup, JC1
Greenfield, CL1
Hungerford, LL1
McKiernan, BC1
Whiteley, HE1
Holladay, JR1

Trials

1 trial available for doxapram and Canine Diseases

ArticleYear
Comparison of the effects of alfaxalone and propofol with acepromazine, butorphanol and/or doxapram on laryngeal motion and quality of examination in dogs.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:3

    Topics: Acepromazine; Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Butorphanol; Cross-Over Studi

2018

Other Studies

5 other studies available for doxapram and Canine Diseases

ArticleYear
Effects of obesity on lung function and airway reactivity in healthy dogs.
    Veterinary journal (London, England : 1997), 2012, Volume: 193, Issue:1

    Topics: Animals; Bronchial Provocation Tests; Bronchoconstriction; Dog Diseases; Dogs; Doxapram; Injections,

2012
Effects of doxapram HCl on laryngeal function of normal dogs and dogs with naturally occurring laryngeal paralysis.
    Veterinary anaesthesia and analgesia, 2004, Volume: 31, Issue:4

    Topics: Animals; Central Nervous System Stimulants; Dog Diseases; Dogs; Doxapram; Female; Infusions, Intrave

2004
Doxapram for reversing xylazine sedation.
    Journal of the American Veterinary Medical Association, 1984, Feb-01, Volume: 184, Issue:3

    Topics: Anesthesia; Animals; Dog Diseases; Dogs; Doxapram; Thiazines; Xylazine

1984
Comparison of unilateral arytenoid lateralization and ventral ventriculocordectomy for the treatment of experimentally induced laryngeal paralysis in dogs.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1997, Volume: 38, Issue:5

    Topics: Animals; Carbon Dioxide; Dog Diseases; Dogs; Doxapram; Laryngoscopy; Postoperative Period; Respirati

1997
Routine use of doxapram hydrochloride in neonatal pups delivered by cesarean section.
    Veterinary medicine, small animal clinician : VM, SAC, 1971, Volume: 66, Issue:1

    Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Cesarean Section; Dog Diseases; Dogs; Doxapram; Fema

1971