Page last updated: 2024-10-26

doxapram and Anxiety

doxapram has been researched along with Anxiety in 1 studies

Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Doxapram at 4 mg/kg increased anxiety-related behaviors in all four anxiety models."3.72Rodent doxapram model of panic: behavioral effects and c-Fos immunoreactivity in the amygdala. ( Apergis, J; Gorman, JM; LeDoux, JE; Sullivan, GM, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sullivan, GM1
Apergis, J1
Gorman, JM1
LeDoux, JE1

Other Studies

1 other study available for doxapram and Anxiety

ArticleYear
Rodent doxapram model of panic: behavioral effects and c-Fos immunoreactivity in the amygdala.
    Biological psychiatry, 2003, May-15, Volume: 53, Issue:10

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Brain; Central Nervous System Stimulants; Conditioning

2003