doxapram has been researched along with Airflow Obstruction, Chronic in 3 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute-on-chronic respiratory failure is becoming an increasingly common medical emergency, mostly as a result of exacerbations of chronic obstructive pulmonary disease." | 2.44 | Managing acute on chronic respiratory failure: a guide to non-invasive ventilation. ( Goldring, JJ; Wedzicha, JA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldring, JJ | 1 |
| Wedzicha, JA | 1 |
| Johnson, MK | 1 |
| Stevenson, RD | 1 |
3 reviews available for doxapram and Airflow Obstruction, Chronic
| Article | Year |
|---|---|
Managing acute on chronic respiratory failure: a guide to non-invasive ventilation.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Doxapram; Humans; Midd | 2008 |
Towards evidence based emergency medicine:PRIVATE best BETs from the Manchester Royal Infirmary. Bet 2: doxapram resurrected? Weak evidence of efficacy suggests a potential use in patients ineligible for non-invasive ventilation.
Topics: Adult; Aged; Doxapram; Emergency Medicine; Evidence-Based Emergency Medicine; Humans; Pulmonary Dise | 2012 |
Management of an acute exacerbation of copd: are we ignoring the evidence?
Topics: Acute Disease; Aged; Antioxidants; Bronchodilator Agents; Doxapram; Expectorants; Glucocorticoids; H | 2002 |