doxapram has been researched along with Acute Disease in 8 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute-on-chronic respiratory failure is becoming an increasingly common medical emergency, mostly as a result of exacerbations of chronic obstructive pulmonary disease." | 2.44 | Managing acute on chronic respiratory failure: a guide to non-invasive ventilation. ( Goldring, JJ; Wedzicha, JA, 2008) |
| "Doxapram is a respiratory stimulant used to stimulate respiration in this setting." | 2.42 | Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease. ( Greenstone, M; Lasserson, TJ, 2003) |
| "Doxapram is a respiratory stimulant used to stimulate breathing in this setting." | 2.41 | Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease. ( Greenstone, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldring, JJ | 1 |
| Wedzicha, JA | 1 |
| Johnson, MK | 1 |
| Stevenson, RD | 1 |
| Greenstone, M | 2 |
| Lasserson, TJ | 1 |
| Fukushima, Y | 1 |
| Houser, WC | 1 |
| Schlueter, DP | 1 |
| Riordan, JF | 1 |
| Sillett, RW | 1 |
| McNicol, MW | 1 |
4 reviews available for doxapram and Acute Disease
| Article | Year |
|---|---|
Managing acute on chronic respiratory failure: a guide to non-invasive ventilation.
Topics: Acute Disease; Aged; Anti-Bacterial Agents; Chronic Disease; Cystic Fibrosis; Doxapram; Humans; Midd | 2008 |
Management of an acute exacerbation of copd: are we ignoring the evidence?
Topics: Acute Disease; Aged; Antioxidants; Bronchodilator Agents; Doxapram; Expectorants; Glucocorticoids; H | 2002 |
Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease.
Topics: Acute Disease; Doxapram; Humans; Lung Diseases, Obstructive; Randomized Controlled Trials as Topic; | 2003 |
Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease.
Topics: Acute Disease; Doxapram; Humans; Lung Diseases, Obstructive; Respiratory Insufficiency; Respiratory | 2000 |
1 trial available for doxapram and Acute Disease
| Article | Year |
|---|---|
A controlled trail of doxapram in acute respiratory failure.
Topics: Acute Disease; Aged; Bronchitis; Carbon Dioxide; Catheterization; Chronic Disease; Clinical Trials a | 1975 |
3 other studies available for doxapram and Acute Disease
| Article | Year |
|---|---|
[Respiratory failure: therapeutic trial on its acute exacerbation].
Topics: Acute Disease; Doxapram; Drug Therapy, Combination; Humans; Respiratory Insufficiency; Spironolacton | 1983 |
Prolonged doxapram infusion in obesity-hypoventilation syndrome.
Topics: Acute Disease; Adult; Doxapram; Female; Humans; Hypoventilation; Infusions, Parenteral; Obesity; Res | 1978 |
Respiratory stimulants.
Topics: Acute Disease; Administration, Oral; Aminobutyrates; Benzamides; Carbon Dioxide; Carbonic Anhydrase | 1972 |