doxapram has been researched along with Acquired Vocal Cord Palsy in 4 studies
Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
doxapram : A member of the class of pyrrolidin-2-ones that is N-ethylpyrrolidin-2-one in which both of the hydrogens at the 3 position (adjacent to the carbonyl group) are substituted by phenyl groups, and one of the hydrogens at the 4 position is substituted by a 2-(morpholin-4-yl)ethyl group. A central and respiratory stimulant with a brief duration of action, it is used (generally as the hydrochloride or the hydrochloride hydrate) as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dogs with laryngeal paralysis may suffer extreme glottic constriction with vigorous respirations, and may require intubation during examination." | 1.32 | Effects of doxapram HCl on laryngeal function of normal dogs and dogs with naturally occurring laryngeal paralysis. ( Harvey, RC; Jackson, AM; Tobias, KM, 2004) |
| "Clinical signs of laryngeal paralysis developed 38 days (median) following denervation." | 1.30 | Bilateral recurrent laryngeal neurectomy as a model for the study of idiopathic canine laryngeal paralysis. ( Alsup, JC; Greenfield, CL; Hungerford, LL; McKiernan, BC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radkey, DI | 1 |
| Hardie, RJ | 1 |
| Smith, LJ | 1 |
| Tobias, KM | 1 |
| Jackson, AM | 1 |
| Harvey, RC | 1 |
| Greenfield, CL | 2 |
| Alsup, JC | 2 |
| Hungerford, LL | 2 |
| McKiernan, BC | 2 |
| Whiteley, HE | 1 |
1 trial available for doxapram and Acquired Vocal Cord Palsy
| Article | Year |
|---|---|
Comparison of the effects of alfaxalone and propofol with acepromazine, butorphanol and/or doxapram on laryngeal motion and quality of examination in dogs.
Topics: Acepromazine; Anesthesia; Anesthetics; Anesthetics, Combined; Animals; Butorphanol; Cross-Over Studi | 2018 |
3 other studies available for doxapram and Acquired Vocal Cord Palsy
| Article | Year |
|---|---|
Effects of doxapram HCl on laryngeal function of normal dogs and dogs with naturally occurring laryngeal paralysis.
Topics: Animals; Central Nervous System Stimulants; Dog Diseases; Dogs; Doxapram; Female; Infusions, Intrave | 2004 |
Bilateral recurrent laryngeal neurectomy as a model for the study of idiopathic canine laryngeal paralysis.
Topics: Animals; Carbon Dioxide; Dogs; Doxapram; Laryngeal Nerves; Male; Postoperative Period; Respiration; | 1997 |
Comparison of unilateral arytenoid lateralization and ventral ventriculocordectomy for the treatment of experimentally induced laryngeal paralysis in dogs.
Topics: Animals; Carbon Dioxide; Dog Diseases; Dogs; Doxapram; Laryngoscopy; Postoperative Period; Respirati | 1997 |