dothiepin-hydrochloride and Shock--Cardiogenic

A case of dothiepin poisoning complicated by cardiogenic shock is described. Hypotension was resistant to conventional inotropes but responded rapidly to high-dose intravenous glucagon. Glucagon should be considered as a useful therapeutic positive inotrope and a potentially antiarrhythmic agent in severe tricyclic antidepressant overdose.

Topics: Adult; Antidepressive Agents, Tricyclic; Cardiotonic Agents; Dothiepin; Drug Administration Schedule; Drug Overdose; Female; Glucagon; Humans; Injections, Intravenous; Shock, Cardiogenic