dorzolamide and Sarcoidosis

dorzolamide has been researched along with Sarcoidosis* in 1 studies

Other Studies

1 other study(ies) available for dorzolamide and Sarcoidosis

ArticleYear
Sarcoidosis patient: an unexpected reaction to carbonic anhydrase enzyme inhibitor.
    BMJ case reports, 2013, Jul-26, Volume: 2013

    Ocular diseases are very common in many of the systemic diseases such as sarcoidosis, and may sometimes be the presenting symptom of the disease. In this case report, we present an unusual reaction of the sarcoid granuloma to carbonic anhydrase enzyme inhibitors (CAIs), which was encountered in a patient with ocular sarcoidosis. This observation was taken after a 2-week interval between a CT scan orbits and an MRI orbits which showed a decrease in size from 4×3×4 cm to 2.5×2.5×2 cm, respectively. We suspected the dorzolamide CAI to have had a significant role in the reduction in size. It is suggested that acidotic changes that occur due to the effect of the carbonic anhydrase inhibitor causes electrolyte imbalance, intracellular as well as extracellular, which lead to the reduction in the size of the granuloma.

    Topics: Carbonic Anhydrase Inhibitors; Eye Diseases; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Sarcoidosis; Sulfonamides; Thiophenes

2013