dorzolamide and Hypertensive-Retinopathy

A young female suffering from chronic kidney disease presented with retinal features suggestive of retinitis pigmentosa (RP). Cystoid intraretinal changes were noted at the macula in both eyes on optical coherence tomography. Careful clinical examination and fluorescein angiography revealed disc oedema, macular hard exudates and flower petal leakage in both eyes. A clinical diagnosis of RP with leaking cystoid macular oedema (CMO) because of hypertensive retinopathy was made. Exudation and macular oedema subsided with hypertension control and posterior sub-Tenon steroid injection. Although CMO does not typically leak on fluorescein angiography in RP, this need not always be true. Clinical signs and fluorescein angiography help in the differentiation of macular oedema when more than one aetiology may be responsible.

Topics: Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Diagnosis, Differential; Female; Fluorescein Angiography; Humans; Hypertensive Retinopathy; Retina; Retinitis Pigmentosa; Sulfonamides; Thiophenes; Tomography, Optical Coherence; Triamcinolone Acetonide; Young Adult