dorzolamide and Eye-Abnormalities

dorzolamide has been researched along with Eye-Abnormalities* in 1 studies

Other Studies

1 other study(ies) available for dorzolamide and Eye-Abnormalities

Article	Year
Congenital glaucoma with acquired peripheral circumferential iris degeneration. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:1 Iris anomalies associated with congenital or early-childhood glaucoma include stable primary developmental abnormalities such as those associated with the Axenfeld-Rieger spectrum and aniridia. Secondary generalized iris atrophy from uncontrolled intraocular pressure is another potential iris finding in pediatric glaucoma. We document an unusual pattern of acquired peripheral circumferential iris degeneration in 2 unrelated children with otherwise-controlled congenital glaucoma. Genetic testing revealed a common homozygous CYP1B1 mutation in one (p.Gly61Glu) and a novel heterozygous FOXC1 deletion in the other (p.Tyr81_Pro95del). Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol	2013

Article

Year

Congenital glaucoma with acquired peripheral circumferential iris degeneration.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:1

Iris anomalies associated with congenital or early-childhood glaucoma include stable primary developmental abnormalities such as those associated with the Axenfeld-Rieger spectrum and aniridia. Secondary generalized iris atrophy from uncontrolled intraocular pressure is another potential iris finding in pediatric glaucoma. We document an unusual pattern of acquired peripheral circumferential iris degeneration in 2 unrelated children with otherwise-controlled congenital glaucoma. Genetic testing revealed a common homozygous CYP1B1 mutation in one (p.Gly61Glu) and a novel heterozygous FOXC1 deletion in the other (p.Tyr81_Pro95del).

Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol

2013