dopamine quinone has been researched along with Parkinson Disease in 20 studies
*Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lavanya, R; Nagashanmugam, KB; Ponnusamy, S; Prabhu, N; Priyatharshni, S; Sivakumar, P | 1 |
| Dijkstra, JM; Ito, S; Nagatsu, T; Nakashima, A; Riederer, P; Wakamatsu, K; Watanabe, H; Wulf, M; Youdim, M; Zecca, L; Zucca, FA | 1 |
| Ho, PGH; Lei, Z; Saw, WT; Tan, EK; Wang, H; Xie, SP; Yi, Z; Zhou, ZD | 1 |
| Goldstein, DS; Isonaka, R; Jinsmaa, Y; Sharabi, Y | 1 |
| Badillo-Ramírez, I; Rivas-Arancibia, S; Saniger, JM | 1 |
| Dukes, AA; Hastings, TG; Hauser, DN; Mortimer, AD | 1 |
| Baranyi, M; Chai, CL; Dunkel, P; Frau, L; Gölöncsér, F; Huleatt, PB; Khoo, ML; Kittel, Á; Kulcsár, S; Mátyus, P; Morelli, M; Otrokocsi, L; Pinna, A; Porceddu, PF; Sperlágh, B | 1 |
| Berman, SB; Hastings, TG; Van Laar, VS | 1 |
| Asanuma, M; Miyazaki, I | 1 |
| Fujimura, T; Hattoria, N; Kubo, S; Mochizuki, H; Taka, H; Wanga, M; Yoritaka, A | 1 |
| Coleman, RA; Green, RL; Lorenz, AN; Sass, MB | 1 |
| Hastings, TG | 1 |
| Arduini, I; Bisaglia, M; Bubacco, L; Mammi, S; Soriano, ME | 1 |
| Belluzzi, E; Beltramini, M; Bisaglia, M; Bubacco, L; Lazzarini, E; Tabares, LC | 1 |
| Asanuma, M; Miyazaki, I; Ogawa, N | 1 |
| Hattori, N; Machida, Y; Noda, K | 1 |
| Cascio, M; Dukes, AA; Hastings, TG; Van Laar, VS | 1 |
| Roskoski, R; Stokes, AH; Vrana, KE; Xu, Y | 1 |
| Chung, BS; Kang, CD; Kim, KW; Kim, SH; Lee, HJ; Lee, HW; Um, JH | 1 |
| Appel, SH; He, Y; Le, W; Ortiz, I; Rowe, D; Xie, W | 1 |
6 review(s) available for dopamine quinone and Parkinson Disease
| Article | Year |
|---|---|
Review on the interactions between dopamine metabolites and α-Synuclein in causing Parkinson's disease.
Topics: alpha-Synuclein; Antioxidants; Dopamine; Humans; Parkinson Disease | 2023 |
The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson's disease.
Topics: Catecholamines; Cysteine; Dopaminergic Neurons; Humans; Melanins; Norepinephrine; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2023 |
5-S-cysteinyl-dopamine, a neurotoxic endogenous metabolite of dopamine: Implications for Parkinson's disease.
Topics: alpha-Synuclein; Biomarkers; Dopamine; Dopaminergic Neurons; Endoplasmic Reticulum Stress; Humans; Metabolic Networks and Pathways; Mitochondria; Nerve Tissue Proteins; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Parkinson Disease; Pars Compacta; Sulfur | 2019 |
Dopaminergic neuron-specific oxidative stress caused by dopamine itself.
Topics: Animals; Disease Models, Animal; Dopamine; Free Radicals; Humans; Neurons; Oxidative Stress; Parkinson Disease | 2008 |
Toxic effects of dopamine metabolism in Parkinson's disease.
Topics: Aldehydes; alpha-Synuclein; Animals; Dopamine; Humans; Levodopa; Mitochondria; Oxidative Stress; Parkinson Disease | 2009 |
Dopamine- or L-DOPA-induced neurotoxicity: the role of dopamine quinone formation and tyrosinase in a model of Parkinson's disease.
Topics: Animals; Dopamine; Dopamine Agents; Free Radicals; Humans; Levodopa; Monophenol Monooxygenase; Neurotoxicity Syndromes; Parkinson Disease | 2003 |
14 other study(ies) available for dopamine quinone and Parkinson Disease
| Article | Year |
|---|---|
The Therapeutic Implications of Tea Polyphenols Against Dopamine (DA) Neuron Degeneration in Parkinson's Disease (PD).
Topics: Animals; Dopamine; Dopaminergic Neurons; Drosophila; HEK293 Cells; Humans; Nerve Degeneration; Parkinson Disease; Plant Extracts; Polyphenols; Tea | 2019 |
3,4-Dihydroxyphenylacetaldehyde Is More Efficient than Dopamine in Oligomerizing and Quinonizing
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; alpha-Synuclein; Antioxidants; Cell Line; Copper; Dopamine; Humans; Monoamine Oxidase; Monophenol Monooxygenase; Oligodendroglia; Oxidation-Reduction; Parkinson Disease; Protein Binding; Protein Conformation; Tolcapone | 2020 |
Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.
Topics: Animals; Blotting, Western; Dopamine; Dopaminergic Neurons; Glutathione Peroxidase; In Vitro Techniques; Parkinson Disease; PC12 Cells; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats | 2013 |
Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Oxidative Stress; Pargyline; Parkinson Disease; Propylamines; Rats, Wistar; Substantia Nigra | 2016 |
Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone.
Topics: Animals; Cell Death; Dopamine; Dopaminergic Neurons; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Muscle Proteins; Parkinson Disease; PC12 Cells; Rats; Rotenone | 2016 |
A pragmatic approach to biochemical systems theory applied to an alpha-synuclein-based model of Parkinson's disease.
Topics: alpha-Synuclein; Amyloid; Antiparkinson Agents; Computer Simulation; Dopamine; Gene Expression; Humans; Levodopa; Lewy Bodies; Lysosomes; Models, Neurological; Monoamine Oxidase Inhibitors; Neurotoxins; Parkinson Disease; Proteasome Endopeptidase Complex; Reactive Oxygen Species; Systems Theory; Ubiquitin | 2009 |
The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease.
Topics: Animals; Dopamine; Humans; Mitochondria; Neurons; Oxidation-Reduction; Parkinson Disease; Proteome; Substantia Nigra | 2009 |
Molecular characterization of dopamine-derived quinones reactivity toward NADH and glutathione: implications for mitochondrial dysfunction in Parkinson disease.
Topics: Animals; Dopamine; Glutathione; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mice; Mitochondria, Liver; Mitochondrial Swelling; Models, Biological; NAD; Oxidative Stress; Parkinson Disease; Quinones; Spectrophotometry, Ultraviolet | 2010 |
Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease.
Topics: Catalytic Domain; Dopamine; Enzyme Activation; Humans; Kinetics; Manganese; Mitochondria; Mutation; Parkinson Disease; Protein Binding; Reactive Oxygen Species; Superoxide Dismutase | 2012 |
[Pathogenesis of Parkinson's disease: a common pathway between alpha-synuclein and parkin and the mechanism of Lewy bodies formation].
Topics: alpha-Synuclein; Animals; Apoptosis; Cells, Cultured; Dihydroxyphenylalanine; Dopamine; Humans; I-kappa B Proteins; Lewy Bodies; NF-KappaB Inhibitor alpha; Parkinson Disease; Phosphorylation; Ubiquitin-Protein Ligases | 2005 |
Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease.
Topics: Animals; Brain; Dopamine; Male; Mitochondria; Mitochondrial Proteins; Oxidative Stress; Parkinson Disease; PC12 Cells; Proteomics; Rats; Rats, Sprague-Dawley | 2008 |
Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase.
Topics: Animals; Antioxidants; Chromatography, Gel; Dihydroxyphenylalanine; Dithiothreitol; Dopamine; Electrophoresis, Polyacrylamide Gel; Feedback; Glutathione; Monophenol Monooxygenase; NAD; Neoplasm Proteins; Nerve Tissue Proteins; Parkinson Disease; PC12 Cells; Plant Proteins; Precipitin Tests; Rats; Tyrosine 3-Monooxygenase | 1998 |
Antiapoptotic role of NF-kappaB in the auto-oxidized dopamine-induced apoptosis of PC12 cells.
Topics: Animals; Apoptosis; Cell Death; DNA; DNA-Binding Proteins; Dopamine; Genes, Dominant; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Parkinson Disease; PC12 Cells; Pheochromocytoma; Rats; Transcription Factor RelA; Transfection | 2001 |
Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease.
Topics: Adult; Aged; Animals; Cell Membrane; Cells, Cultured; Cytokines; Dopamine; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Immunoglobulin Fab Fragments; Immunoglobulin G; Lipopolysaccharides; Mice; Mice, Knockout; Microglia; Middle Aged; Neurons; Nitric Oxide; Oxidative Stress; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, IgG | 2001 |