Page last updated: 2024-10-26

donepezil and Urinary Bladder, Overactive

donepezil has been researched along with Urinary Bladder, Overactive in 3 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Urinary Bladder, Overactive: Symptom of overactive detrusor muscle of the URINARY BLADDER that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. URINARY INCONTINENCE may or may not be present.

Research Excerpts

ExcerptRelevanceReference
" The study included older adults (aged 65 and older) with a diagnosis of dementia using donepezil, galantamine, or rivastigmine."4.12Risk of overactive bladder associated with cholinesterase inhibitors in dementia. ( Aparasu, RR; Chatterjee, S; Chen, H; Johnson, ML; Masurkar, PP; Sherer, JT, 2022)
"Left middle cerebral artery occlusion (MCAO) was performed in female Sprague-Dawley rats."1.33Acetylcholinesterase inhibitor acting on the brain improves detrusor overactivity caused by cerebral infarction in rats. ( Akino, H; Aoki, Y; Ito, H; Kaneda, T; Matsuta, Y; Miwa, Y; Nakai, M; Oyama, N; Shiyama, R; Tanase, K; Yokoyama, O, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Masurkar, PP1
Chatterjee, S1
Sherer, JT1
Chen, H1
Johnson, ML1
Aparasu, RR1
Sakakibara, R1
Ogata, T1
Uchiyama, T1
Kishi, M1
Ogawa, E1
Isaka, S1
Yuasa, J1
Yamamoto, T1
Ito, T1
Yamanishi, T1
Awa, Y1
Yamaguchi, C1
Takahashi, O1
Nakai, M1
Akino, H1
Kaneda, T1
Matsuta, Y1
Shiyama, R1
Tanase, K1
Ito, H1
Aoki, Y1
Oyama, N1
Miwa, Y1
Yokoyama, O1

Other Studies

3 other studies available for donepezil and Urinary Bladder, Overactive

ArticleYear
Risk of overactive bladder associated with cholinesterase inhibitors in dementia.
    Journal of the American Geriatrics Society, 2022, Volume: 70, Issue:3

    Topics: Aged; Cholinesterase Inhibitors; Dementia; Donepezil; Female; Galantamine; Humans; Male; Medicare; M

2022
How to manage overactive bladder in elderly individuals with dementia? A combined use of donepezil, a central acetylcholinesterase inhibitor, and propiverine, a peripheral muscarine receptor antagonist.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:8

    Topics: Aged; Aged, 80 and over; Benzilates; Chi-Square Distribution; Cholinergic Antagonists; Cholinesteras

2009
Acetylcholinesterase inhibitor acting on the brain improves detrusor overactivity caused by cerebral infarction in rats.
    Neuroscience, 2006, Oct-13, Volume: 142, Issue:2

    Topics: Analysis of Variance; Animals; Brain; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Donepe

2006