donepezil has been researched along with Tauopathies in 3 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Tauopathies: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Guyot, AC | 1 |
| Leuxe, C | 1 |
| Disdier, C | 1 |
| Oumata, N | 1 |
| Costa, N | 1 |
| Roux, GL | 1 |
| Varela, PF | 1 |
| Duchon, A | 1 |
| Charbonnier, JB | 1 |
| Herault, Y | 1 |
| Pavoni, S | 1 |
| Galons, H | 1 |
| Andriambeloson, E | 1 |
| Wagner, S | 1 |
| Meijer, L | 1 |
| Lund, AK | 1 |
| Mabondzo, A | 1 |
| Yoshiyama, Y | 1 |
| Kojima, A | 1 |
| Ishikawa, C | 1 |
| Arai, K | 1 |
| Ballard, CG | 1 |
| Chalmers, KA | 1 |
| Todd, C | 1 |
| McKeith, IG | 1 |
| O'Brien, JT | 1 |
| Wilcock, G | 1 |
| Love, S | 1 |
| Perry, EK | 1 |
3 other studies available for donepezil and Tauopathies
| Article | Year |
|---|---|
A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment.
Topics: Aging; Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Cognition Disorders; Donepezil; Drug Ev | 2020 |
Anti-inflammatory action of donepezil ameliorates tau pathology, synaptic loss, and neurodegeneration in a tauopathy mouse model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Donepezil; Humans; Indans; | 2010 |
Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.
Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Autopsy; Cerebral Cortex; Cholinesterase Inhibitors; | 2007 |