donepezil has been researched along with Sleep Initiation and Maintenance Disorders in 5 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(1) Donepezil can reduce memory loss, dry mouth, and constipation in nongeriatric affective patients, but may trigger mania; and (2) long-term follow-up will reveal the predictive value for dementia of donepezil's memory restoration in nongeriatric subjects." | 5.09 | Donepezil for psychotropic-induced memory loss. ( Comas-Díaz, L; Jacobsen, FM, 1999) |
| "While these drugs are known to induce classic cholinergic adverse events such as diarrhea, their potential to cause psychiatric adverse events has yet to be thoroughly examined." | 3.01 | Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis. ( Algharably, EEA; Bermpohl, F; Bittner, N; Brandl, EJ; Funk, CSM; Kreutz, R; Riemer, TG; Schmidt, A, 2023) |
| " Adverse events (AEs) were recorded throughout." | 2.75 | Safety and tolerability of donepezil in mild cognitive impairment: open-label extension study. ( Doody, RS; Ferris, S; Gao, J; Goldman, R; Murthy, AK; Salloway, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bittner, N | 1 |
| Funk, CSM | 1 |
| Schmidt, A | 1 |
| Bermpohl, F | 1 |
| Brandl, EJ | 1 |
| Algharably, EEA | 1 |
| Kreutz, R | 1 |
| Riemer, TG | 1 |
| Segrec, N | 1 |
| Zaman, R | 1 |
| Pregelj, P | 1 |
| Doody, RS | 1 |
| Ferris, S | 1 |
| Salloway, S | 1 |
| Goldman, R | 1 |
| Gao, J | 1 |
| Murthy, AK | 1 |
| Carrier, L | 1 |
| Jacobsen, FM | 1 |
| Comas-Díaz, L | 1 |
1 review available for donepezil and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis.
Topics: Acetylcholinesterase; Alzheimer Disease; Anorexia; Cholinesterase Inhibitors; Donepezil; Galantamine | 2023 |
2 trials available for donepezil and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Safety and tolerability of donepezil in mild cognitive impairment: open-label extension study.
Topics: Adult; Aged; Aged, 80 and over; Amnesia; Cholinesterase Inhibitors; Cognition Disorders; Diarrhea; D | 2010 |
Donepezil for psychotropic-induced memory loss.
Topics: Adult; Ambulatory Care; Cholinesterase Inhibitors; Constipation; Depressive Disorder; Diarrhea; Dizz | 1999 |
2 other studies available for donepezil and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Increased libido associated with donepezil treatment: a case report.
Topics: Alzheimer Disease; Antidepressive Agents, Tricyclic; Cholinesterase Inhibitors; Donepezil; Dose-Resp | 2016 |
Donepezil and paroxetine: possible drug interaction.
Topics: Aged; Aggression; Akathisia, Drug-Induced; Antidepressive Agents, Second-Generation; Confusion; Diar | 1999 |