donepezil has been researched along with REM Sleep Behavior Disorder in 4 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
REM Sleep Behavior Disorder: A disorder characterized by episodes of vigorous and often violent motor activity during REM sleep (SLEEP, REM). The affected individual may inflict self injury or harm others, and is difficult to awaken from this condition. Episodes are usually followed by a vivid recollection of a dream that is consistent with the aggressive behavior. This condition primarily affects adult males. (From Adams et al., Principles of Neurology, 6th ed, p393)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported." | 5.31 | Treatment of REM sleep behavior disorder with donepezil: a report of three cases. ( Ringman, JM; Simmons, JH, 2000) |
| "Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported." | 1.31 | Treatment of REM sleep behavior disorder with donepezil: a report of three cases. ( Ringman, JM; Simmons, JH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stær, K | 1 |
| Iranzo, A | 1 |
| Stokholm, MG | 1 |
| Østergaard, K | 1 |
| Serradell, M | 1 |
| Otto, M | 1 |
| Svendsen, KB | 1 |
| Garrido, A | 1 |
| Vilas, D | 1 |
| Santamaria, J | 1 |
| Møller, A | 1 |
| Gaig, C | 1 |
| Brooks, DJ | 1 |
| Borghammer, P | 1 |
| Tolosa, E | 1 |
| Pavese, N | 1 |
| Ozaki, A | 1 |
| Nishida, M | 1 |
| Koyama, K | 1 |
| Ishikawa, K | 1 |
| Nishikawa, T | 1 |
| Massironi, G | 1 |
| Galluzzi, S | 1 |
| Frisoni, GB | 1 |
| Ringman, JM | 1 |
| Simmons, JH | 1 |
4 other studies available for donepezil and REM Sleep Behavior Disorder
| Article | Year |
|---|---|
Cortical cholinergic dysfunction correlates with microglial activation in the substantia innominata in REM sleep behavior disorder.
Topics: Acetylcholinesterase; Aged; Carbon Radioisotopes; Cerebral Cortex; Cholinesterase Inhibitors; Cognit | 2020 |
Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies: a case report.
Topics: Aged, 80 and over; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Humans; Indans; Lewy Bod | 2012 |
Drug treatment of REM sleep behavior disorders in dementia with Lewy bodies.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Benzodiazepines; Cholinesterase Inhibitors; Clonazepam; Do | 2003 |
Treatment of REM sleep behavior disorder with donepezil: a report of three cases.
Topics: Adult; Aged; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Male; Middle Aged; Piperidines; P | 2000 |