Page last updated: 2024-10-26

donepezil and Parkinsonian Disorders

donepezil has been researched along with Parkinsonian Disorders in 9 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Research Excerpts

ExcerptRelevanceReference
"She was diagnosed as having parkinsonism and took medication."5.32[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report]. ( Kondo, T; Miwa, H; Morita, S, 2004)
"She was diagnosed as having parkinsonism and took medication."1.32[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report]. ( Kondo, T; Miwa, H; Morita, S, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Wang, HM1
Liou, LM1
Hsu, CY1
Lin, HF1
Hawlitschka, A1
Holzmann, C1
Wree, A1
Antipova, V1
Thomas Antérion, C1
Convers, P1
Desmales, S1
Borg, C1
Laurent, B1
Kawahira, K1
Noma, T1
Iiyama, J1
Etoh, S1
Ogata, A1
Shimodozono, M1
Shiio, Y1
Hager, K1
Calabrese, P1
Frölich, L1
Göbel, C1
Berger, FM1
Rozzini, L1
Ghianda, D1
Trabucchi, M1
Padovani, A1
Morita, S1
Miwa, H1
Kondo, T1
Arai, M1

Other Studies

9 other studies available for donepezil and Parkinsonian Disorders

ArticleYear
Letter to the editor: Donepezil-induced parkinsonism in end-stage renal disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:11

    Topics: Aged; Donepezil; Female; Humans; Kidney Failure, Chronic; Parkinsonian Disorders

2021
Repeated Intrastriatal Botulinum Neurotoxin-A Injection in Hemiparkinsonian Rats Increased the Beneficial Effect on Rotational Behavior.
    Toxins, 2018, 09-11, Volume: 10, Issue:9

    Topics: Animals; Apomorphine; Behavior, Animal; Botulinum Toxins, Type A; Corpus Striatum; Donepezil; Inject

2018
An odd manifestation of the Capgras syndrome: loss of familiarity even with the sexual partner.
    Neurophysiologie clinique = Clinical neurophysiology, 2008, Volume: 38, Issue:3

    Topics: Aged; Amnesia; Antipsychotic Agents; Atrophy; Brain; Capgras Syndrome; Donepezil; Hallucinations; Hu

2008
Improvements in limb kinetic apraxia by repetition of a newly designed facilitation exercise in a patient with corticobasal degeneration.
    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2009, Volume: 32, Issue:2

    Topics: Activities of Daily Living; Apraxia, Ideomotor; Cholinesterase Inhibitors; Disease Progression; Done

2009
[Drug induced parkinsonism].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

    Topics: Antipsychotic Agents; Benzamides; Butyrophenones; Calcium Channel Blockers; Cholinesterase Inhibitor

2012
An observational clinical study of the efficacy and tolerability of donepezil in the treatment of Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2003, Volume: 15, Issue:4

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibi

2003
Severe worsening of parkinsonism in Lewy body dementia due to donepezil.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Acetylcholine; Aged; Basal Ganglia; Cholinesterase Inhibitors; Disease Progression; Donepezil; Dopam

2004
[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report].
    No to shinkei = Brain and nerve, 2004, Volume: 56, Issue:10

    Topics: Aged; Catatonia; Donepezil; Female; Hallucinations; Humans; Indans; Lewy Body Disease; Nootropic Age

2004
Parkinsonism onset in a patient concurrently using tiapride and donepezil.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:10

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Dopamine Antagonists; Drug Therapy, Combination; Female;

2000