donepezil has been researched along with Movement Disorders in 5 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil was increased to 10 mg, and 2 months later, the patient developed dropped head syndrome." | 1.91 | [Abnormal posture of the trunk related to donepezil hydrochloride: report of 2 cases]. ( Komatsu, K; Takahashi, M; Ueda, A, 2023) |
| "Donepezil treatment reduced cholesterol accumulation in adult neural stem cells in vitro, and it downregulated the expression of the cholesterol synthesis factors' sterol regulatory element-binding proteins and 3-hydroxy-3-methylglutaryl-CoA reductase in the cerebellum, implying that AChE activity might be associated with cholesterol homeostasis." | 1.40 | Donepezil enhances Purkinje cell survival and alleviates motor dysfunction by inhibiting cholesterol synthesis in a murine model of Niemann Pick disease type C. ( Choi, SW; Hong, IS; Kang, I; Kang, KS; Kim, HS; Seo, Y; Shin, Y; Yu, KR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ueda, A | 1 |
| Komatsu, K | 1 |
| Takahashi, M | 1 |
| Seo, Y | 1 |
| Shin, Y | 1 |
| Kim, HS | 1 |
| Kang, I | 1 |
| Hong, IS | 1 |
| Choi, SW | 1 |
| Yu, KR | 1 |
| Kang, KS | 1 |
| Thomas Antérion, C | 1 |
| Convers, P | 1 |
| Desmales, S | 1 |
| Borg, C | 1 |
| Laurent, B | 1 |
| Leelavathi, M | 1 |
| Rosdinom, R | 1 |
| Suguna, M | 1 |
| Amouyal-Barkate, K | 1 |
| Bagheri-Charabiani, H | 1 |
| Montastruc, JL | 1 |
| Moulias, S | 1 |
| Vellas, B | 1 |
5 other studies available for donepezil and Movement Disorders
| Article | Year |
|---|---|
[Abnormal posture of the trunk related to donepezil hydrochloride: report of 2 cases].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Female; Humans; In | 2023 |
Donepezil enhances Purkinje cell survival and alleviates motor dysfunction by inhibiting cholesterol synthesis in a murine model of Niemann Pick disease type C.
Topics: Adult Stem Cells; Animals; ATP-Binding Cassette Transporters; Cell Survival; Cells, Cultured; Cerebe | 2014 |
An odd manifestation of the Capgras syndrome: loss of familiarity even with the sexual partner.
Topics: Aged; Amnesia; Antipsychotic Agents; Atrophy; Brain; Capgras Syndrome; Donepezil; Hallucinations; Hu | 2008 |
Pisa syndrome secondary to rivastigmine: a case report.
Topics: Aged; Benzodiazepines; Cholinesterase Inhibitors; Delusions; Dementia; Donepezil; Humans; Indans; Ma | 2012 |
Abnormal movements with donepezil in Alzheimer disease.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Hum | 2000 |