donepezil has been researched along with Long QT Syndrome in 7 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine has been widely prescribed to treat patients with COVID-19 pneumonia." | 1.62 | Torsades de pointes in SARS-CoV-2 (COVID-19) pneumonia: medicine reconciliation and careful monitoring of QTc interval may help prevent cardiac complications. ( Ali, N; Aslam, W; Lamb, CR, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Kho, J | 1 |
| Ioannou, A | 1 |
| Mandal, AKJ | 1 |
| Cox, A | 1 |
| Nasim, A | 1 |
| Metaxa, S | 1 |
| Missouris, CG | 1 |
| Aslam, W | 1 |
| Lamb, CR | 1 |
| Ali, N | 1 |
| Jackson, EG | 1 |
| Stowe, S | 1 |
| Malik, BH | 1 |
| Kitt, J | 1 |
| Irons, R | 1 |
| Al-Obaidi, M | 1 |
| Missouris, C | 1 |
| Takaya, T | 1 |
| Okamoto, M | 1 |
| Yodoi, K | 1 |
| Hata, K | 1 |
| Kijima, Y | 1 |
| Nakajima, H | 1 |
| Nishikawa, Y | 1 |
| Kita, T | 1 |
| Ito, M | 1 |
| Seo, T | 1 |
| Kawashima, S | 1 |
| Leitch, A | 1 |
| McGinness, P | 1 |
| Wallbridge, D | 1 |
7 other studies available for donepezil and Long QT Syndrome
| Article | Year |
|---|---|
Long term use of donepezil and QTc prolongation.
Topics: Aged, 80 and over; Alzheimer Disease; Donepezil; Electrocardiography; Female; Heart Rate; Humans; Lo | 2021 |
Torsades de pointes in SARS-CoV-2 (COVID-19) pneumonia: medicine reconciliation and careful monitoring of QTc interval may help prevent cardiac complications.
Topics: Aged; Anti-Infective Agents; Citalopram; COVID-19 Drug Treatment; Dexamethasone; Donepezil; Drug The | 2021 |
Lesson of the month 1: Prolonged QT syndrome due to donepezil: a reversible cause of falls?
Topics: Accidental Falls; Aged, 80 and over; Alzheimer Disease; Donepezil; Female; Humans; Long QT Syndrome; | 2019 |
Donepezil - QT prolongation and torsades de pointes.
Topics: Accidental Falls; Arrhythmias, Cardiac; Donepezil; Humans; Long QT Syndrome; Torsades de Pointes | 2019 |
A case of donepezil-related torsades de pointes.
Topics: Aged, 80 and over; Alzheimer Disease; Cardiopulmonary Resuscitation; Donepezil; Electrocardiography; | 2015 |
Torsades de Pointes with QT prolongation related to donepezil use.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Colitis; Donepezil; Electrocardiogr | 2009 |
Calculate the QT interval in patients taking drugs for dementia.
Topics: Aged; Dementia; Donepezil; Female; Humans; Indans; Long QT Syndrome; Nootropic Agents; Piperidines; | 2007 |