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donepezil and Liver Failure, Acute

donepezil has been researched along with Liver Failure, Acute in 1 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.

Research Excerpts

ExcerptRelevanceReference
"Treatment with sertraline was initiated in February 1998."1.31Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy. ( Nace, DA; Towers, AL; Verrico, MM, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verrico, MM1
Nace, DA1
Towers, AL1

Other Studies

1 other study available for donepezil and Liver Failure, Acute

ArticleYear
Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy.
    Journal of the American Geriatrics Society, 2000, Volume: 48, Issue:12

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Alzheimer Disease; Bilirubin; Biopsy; Chemical and Dr

2000