donepezil has been researched along with Liver Cirrhosis in 1 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil was equally well tolerated by all subjects." | 2.69 | An evaluation of the pharmacokinetics of donepezil HCl in patients with impaired hepatic function. ( Friedhoff, LT; Perdomo, CA; Tiseo, PJ; Vargas, R, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tiseo, PJ | 1 |
| Vargas, R | 1 |
| Perdomo, CA | 1 |
| Friedhoff, LT | 1 |
1 trial available for donepezil and Liver Cirrhosis
| Article | Year |
|---|---|
An evaluation of the pharmacokinetics of donepezil HCl in patients with impaired hepatic function.
Topics: Administration, Oral; Adult; Aged; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; | 1998 |