donepezil has been researched along with Kidney Diseases in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil was well tolerated by both groups." | 2.71 | Steady-state pharmacokinetics and safety of donepezil HCl in subjects with moderately impaired renal function. ( Bolton, WK; Cullen, EI; Gutierrez, MJ; Hutman, HW; Kumar, D; Marbury, TC; Nagy, CF; Pratt, RD, 2004) |
| " Blood samples for pharmacokinetic measurements were taken at specified intervals for 17 days post-dose." | 2.69 | An evaluation of the pharmacokinetics of donepezil HCl in patients with moderately to severely impaired renal function. ( Foley, K; Friedhoff, LT; Tiseo, PJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagy, CF | 1 |
| Kumar, D | 1 |
| Cullen, EI | 1 |
| Bolton, WK | 1 |
| Marbury, TC | 1 |
| Gutierrez, MJ | 1 |
| Hutman, HW | 1 |
| Pratt, RD | 1 |
| Tiseo, PJ | 1 |
| Foley, K | 1 |
| Friedhoff, LT | 1 |
2 trials available for donepezil and Kidney Diseases
| Article | Year |
|---|---|
Steady-state pharmacokinetics and safety of donepezil HCl in subjects with moderately impaired renal function.
Topics: Adult; Aged; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Female; Humans; Indans; Kidney Di | 2004 |
An evaluation of the pharmacokinetics of donepezil HCl in patients with moderately to severely impaired renal function.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Cholinesterase Inhibitors; Donepezil; Femal | 1998 |