donepezil has been researched along with Intraocular Pressure in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil, a selective acetylcholinesterase (AChE) inhibitor, has been shown to reduce intraocular pressure (IOP) in ocular normotensive rabbit eyes." | 7.73 | Effect of oral donepezil on intraocular pressure in normotensive Alzheimer patients. ( Berkhoff, M; Cattapan-Ludewig, K; Daepp, GC; Estermann, S; Frueh, BE; Goldblum, D, 2006) |
| "Donepezil, a selective acetylcholinesterase (AChE) inhibitor, has been shown to reduce intraocular pressure (IOP) in ocular normotensive rabbit eyes." | 3.73 | Effect of oral donepezil on intraocular pressure in normotensive Alzheimer patients. ( Berkhoff, M; Cattapan-Ludewig, K; Daepp, GC; Estermann, S; Frueh, BE; Goldblum, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshida, Y | 1 |
| Sugiyama, T | 1 |
| Utsunomiya, K | 1 |
| Ogura, Y | 1 |
| Ikeda, T | 1 |
| Estermann, S | 1 |
| Daepp, GC | 1 |
| Cattapan-Ludewig, K | 1 |
| Berkhoff, M | 1 |
| Frueh, BE | 1 |
| Goldblum, D | 1 |
2 other studies available for donepezil and Intraocular Pressure
| Article | Year |
|---|---|
A pilot study for the effects of donepezil therapy on cerebral and optic nerve head blood flow, visual field defect in normal-tension glaucoma.
Topics: Administration, Oral; Aged; Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cholinesterase | 2010 |
Effect of oral donepezil on intraocular pressure in normotensive Alzheimer patients.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepez | 2006 |