donepezil has been researched along with Insulin Resistance in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, we tested the hypothesis that donepezil would attenuate central inflammation and oxidative damage and improve memory deficit in high-fat diet (HFD)-fed mice." | 7.91 | Donepezil Attenuates Obesity-Associated Oxidative Stress and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet. ( Chen, J; Fu, X; Jiang, L; Ren, H; Su, L; Wang, C; Wang, Y, 2019) |
| "In this study, we tested the hypothesis that donepezil would attenuate central inflammation and oxidative damage and improve memory deficit in high-fat diet (HFD)-fed mice." | 3.91 | Donepezil Attenuates Obesity-Associated Oxidative Stress and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet. ( Chen, J; Fu, X; Jiang, L; Ren, H; Su, L; Wang, C; Wang, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, L | 1 |
| Wang, Y | 1 |
| Su, L | 1 |
| Ren, H | 1 |
| Wang, C | 1 |
| Chen, J | 1 |
| Fu, X | 1 |
| Gomaa, AA | 1 |
| Makboul, RM | 1 |
| El-Mokhtar, MA | 1 |
| Abdel-Rahman, EA | 1 |
| Ahmed, EA | 1 |
| Nicola, MA | 1 |
2 other studies available for donepezil and Insulin Resistance
| Article | Year |
|---|---|
Donepezil Attenuates Obesity-Associated Oxidative Stress and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet.
Topics: Animals; Diet, High-Fat; Donepezil; Glycation End Products, Advanced; Inflammation; Insulin Resistan | 2019 |
Evaluation of the neuroprotective effect of donepezil in type 2 diabetic rats.
Topics: Alzheimer Disease; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Donepezil; H | 2021 |