donepezil has been researched along with Injury, Myocardial Reperfusion in 3 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil plays a neuroprotective role in I/R‑associated diseases." | 1.72 | Donepezil ameliorates oxygen‑glucose deprivation/reoxygenation‑induced cardiac microvascular endothelial cell dysfunction through PARP1/NF‑κB signaling. ( Li, Y; Sun, X; Wang, J; Yang, C; Zhuang, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Sun, X | 1 |
| Zhuang, J | 1 |
| Wang, J | 1 |
| Yang, C | 1 |
| Ongnok, B | 1 |
| Khuanjing, T | 2 |
| Chunchai, T | 1 |
| Kerdphoo, S | 2 |
| Jaiwongkam, T | 2 |
| Chattipakorn, N | 2 |
| Chattipakorn, SC | 2 |
| Palee, S | 1 |
| Anomasiri, A | 1 |
3 other studies available for donepezil and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Donepezil ameliorates oxygen‑glucose deprivation/reoxygenation‑induced cardiac microvascular endothelial cell dysfunction through PARP1/NF‑κB signaling.
Topics: Adolescent; Adult; Apoptosis; Cell Line; Cell Survival; Donepezil; Endothelial Cells; Female; Glucos | 2022 |
Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia/reperfusion injury.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Brain Injuries; Disease Mode | 2021 |
Donepezil attenuated cardiac ischemia/reperfusion injury through balancing mitochondrial dynamics, mitophagy, and autophagy.
Topics: Animals; Autophagy; Cholinesterase Inhibitors; Donepezil; Male; Mitochondria, Heart; Mitophagy; Myoc | 2021 |