Page last updated: 2024-10-26

donepezil and Genetic Predisposition

donepezil has been researched along with Genetic Predisposition in 2 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scacchi, R1
Gambina, G1
Broggio, E1
Corbo, RM1
Nozawa, M1
Ichimiya, Y1
Nozawa, E1
Utumi, Y1
Sugiyama, H1
Murayama, N1
Iseki, E1
Arai, H1

Trials

1 trial available for donepezil and Genetic Predisposition

ArticleYear
Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in Japan.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2009, Volume: 9, Issue:2

    Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Cholinesterase Inhibitors; Cognition; Disease Progressio

2009

Other Studies

1 other study available for donepezil and Genetic Predisposition

ArticleYear
Sex and ESR1 genotype may influence the response to treatment with donepezil and rivastigmine in patients with Alzheimer's disease.
    International journal of geriatric psychiatry, 2014, Volume: 29, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Brief Psychiatric Rating Scale; Ch

2014