donepezil has been researched along with Encephalopathy, Traumatic in 4 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, a dose-response study evaluating DON after a controlled cortical impact (CCI) injury in rats did not reveal cognitive benefits." | 1.48 | Systemic administration of donepezil attenuates the efficacy of environmental enrichment on neurobehavioral outcome after experimental traumatic brain injury. ( Bondi, CO; Bou-Abboud, CE; Cheng, JP; Day-Cooney, J; Folweiler, KA; Kline, AE; Leary, JB; Memarzadeh, K; Tehranian-DePasquale, R; Yelleswarapu, NK, 2018) |
| "Donepezil was increased from 5 to 10 mg 7-10 days after initiation and maintained until follow-up cognitive assessment." | 1.48 | The effect of donepezil on the cognitive ability early in the course of recovery from traumatic brain injury. ( Brunner, RC; Campbell, KA; Hollis, SD; Kennedy, RE; Lumsden, RA; Novack, TA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swenson, TL | 1 |
| Roehmer, C | 1 |
| Tran, R | 1 |
| Plummer, C | 1 |
| Florentino, SA | 1 |
| Bawany, MH | 1 |
| Ma, HM | 1 |
| Bondi, CO | 1 |
| Yelleswarapu, NK | 1 |
| Day-Cooney, J | 1 |
| Memarzadeh, K | 1 |
| Folweiler, KA | 1 |
| Bou-Abboud, CE | 1 |
| Leary, JB | 1 |
| Cheng, JP | 1 |
| Tehranian-DePasquale, R | 1 |
| Kline, AE | 1 |
| Campbell, KA | 1 |
| Kennedy, RE | 1 |
| Brunner, RC | 1 |
| Hollis, SD | 1 |
| Lumsden, RA | 1 |
| Novack, TA | 1 |
1 review available for donepezil and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Acetylcholinesterase inhibitors to enhance recovery from traumatic brain injury: a comprehensive review and case series.
Topics: Acetylcholinesterase; Adult; Brain Injuries, Traumatic; Child; Cholinesterase Inhibitors; Donepezil; | 2022 |
3 other studies available for donepezil and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Donepezil for Aphasia After Severe Traumatic Brain Injury: A Clinical Vignette.
Topics: Aphasia; Brain Injuries, Traumatic; Donepezil; Humans | 2022 |
Systemic administration of donepezil attenuates the efficacy of environmental enrichment on neurobehavioral outcome after experimental traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries, Traumatic; Cerebral Cortex; Cognition Disorders; Dise | 2018 |
The effect of donepezil on the cognitive ability early in the course of recovery from traumatic brain injury.
Topics: Adolescent; Adult; Aged; Brain Injuries, Traumatic; Cognition Disorders; Donepezil; Female; Glasgow | 2018 |