donepezil has been researched along with Elevated Cholesterol in 3 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "0 years) with probable or possible VaD, according to National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche en l'Enseignement en Neurosciences criteria, were randomized to receive donepezil 5 mg/day (n = 208), donepezil 10 mg/day (after 5 mg/day for the first 28 days) (n = 215), or placebo (n = 193) for 24 weeks." | 5.10 | Donepezil in vascular dementia: a randomized, placebo-controlled study. ( Doody, R; Helme, R; Kertesz, A; Mintzer, J; Pratt, RD; Taubman, K; Wilkinson, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Machado, AE | 1 |
| de Sousa, G | 1 |
| Mancini, G | 1 |
| Faria, MS | 1 |
| de Bem, AF | 1 |
| Moreira, ELG | 1 |
| Wilkinson, D | 1 |
| Doody, R | 1 |
| Helme, R | 1 |
| Taubman, K | 1 |
| Mintzer, J | 1 |
| Kertesz, A | 1 |
| Pratt, RD | 1 |
| Martínez-Vila, E | 1 |
| Murie-Fernández, M | 1 |
| Gállego Pérez-Larraya, J | 1 |
| Irimia, P | 1 |
1 trial available for donepezil and Elevated Cholesterol
| Article | Year |
|---|---|
Donepezil in vascular dementia: a randomized, placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dementia, Vascular; Donepezil; Double-Bli | 2003 |
2 other studies available for donepezil and Elevated Cholesterol
| Article | Year |
|---|---|
Hypercholesterolemia impairs contextual fear conditioning memory formation in female mice: evidence for cholinergic dysfunction.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cholinesterase Inhibitors; Conditioning, Classical; | 2018 |
Neuroprotection in vascular dementia.
Topics: Animals; Cholinesterase Inhibitors; Dementia, Vascular; Donepezil; Excitatory Amino Acid Antagonists | 2006 |