donepezil has been researched along with Dystonia in 7 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We herein report an 81-year-old woman with Alzheimer's disease (AD) in who donepezil, a cholinesterase inhibitor (ChEI), caused cervical dystonia." | 8.90 | Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors. ( Hanashiro, S; Ikeda, K; Iwasaki, Y; Kawabe, K; Sawada, M; Yanagihashi, M, 2014) |
| "We herein report an 81-year-old woman with Alzheimer's disease (AD) in who donepezil, a cholinesterase inhibitor (ChEI), caused cervical dystonia." | 4.90 | Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors. ( Hanashiro, S; Ikeda, K; Iwasaki, Y; Kawabe, K; Sawada, M; Yanagihashi, M, 2014) |
| "Success in treating patients with progressive supranuclear palsy and corticobasal degeneration remains exceedingly low." | 1.33 | Treatment of progressive supranuclear palsy and corticobasal degeneration. ( Lang, AE, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mukku, SSR | 1 |
| Achary, U | 1 |
| Sivakumar, PT | 1 |
| Varghese, M | 1 |
| Ikeda, K | 1 |
| Yanagihashi, M | 1 |
| Sawada, M | 1 |
| Hanashiro, S | 1 |
| Kawabe, K | 1 |
| Iwasaki, Y | 1 |
| Huvent-Grelle, D | 1 |
| Roche, J | 1 |
| Gaxatte, C | 1 |
| Dewailly, P | 1 |
| Puisieux, F | 1 |
| Ioannidis, P | 1 |
| Maiovis, P | 1 |
| Balamoutsos, G | 1 |
| Karacostas, D | 1 |
| Lang, AE | 1 |
| Kwak, YT | 1 |
| Han, IW | 1 |
| Baik, J | 1 |
| Koo, MS | 1 |
| Miyaoka, T | 1 |
| Seno, H | 1 |
| Yamamori, C | 1 |
| Inagaki, T | 1 |
| Itoga, M | 1 |
| Tsubouchi, K | 1 |
| Horiguchi, J | 1 |
2 reviews available for donepezil and Dystonia
| Article | Year |
|---|---|
Donepezil-induced cervical dystonia in Alzheimer's disease: a case report and literature review of dystonia due to cholinesterase inhibitors.
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dystonia; Female; Humans | 2014 |
[Relation between Pisa syndrome and choline esterase inhibitors in a cohort of Alzheimer's disease patients].
Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cohort Studies; Donepezil; Dystonia | 2009 |
5 other studies available for donepezil and Dystonia
| Article | Year |
|---|---|
Recurrent truncal dystonia (Pisa syndrome) due to donepezil - A case report.
Topics: Cholinesterase Inhibitors; Dementia; Donepezil; Dystonia; Humans; Male; Middle Aged; Syndrome | 2018 |
Acute Pisa syndrome after administration of a single dose of donepezil.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dystonia; Female; Humans; Indans; Mem | 2012 |
Treatment of progressive supranuclear palsy and corticobasal degeneration.
Topics: Amantadine; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Donepezil; Dopamine Agents; | 2005 |
Relation between cholinesterase inhibitor and Pisa syndrome.
Topics: Aged; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Donepezil; Dopamine Antagonists; Dys | 2000 |
Pisa syndrome due to a cholinesterase inhibitor (donepezil): a case report.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Dystonia; Humans; Indans; Male; Middle Aged | 2001 |