donepezil has been researched along with Drug Withdrawal Symptoms in 5 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When donepezil was re-prescribed, the delirium resolved and the patient's mental state stabilized." | 5.38 | Withdrawal syndrome after donepezil cessation in a patient with dementia. ( Bidzan, L; Bidzan, M, 2012) |
| "When donepezil was re-prescribed, the delirium resolved and the patient's mental state stabilized." | 1.38 | Withdrawal syndrome after donepezil cessation in a patient with dementia. ( Bidzan, L; Bidzan, M, 2012) |
| "Remarkably, acetylcholinesterase (AChE) inhibitors that act on the brain AChE suppressed both cocaine- and morphine-induced conditioned place preference and blocked the induction and persistence of cocaine-evoked hyperlocomotion." | 1.32 | Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine. ( Hikida, T; Kitabatake, Y; Nakanishi, S; Pastan, I, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poole, RL | 1 |
| Connor, DA | 1 |
| Gould, TJ | 1 |
| Le Cozannet, R | 1 |
| Fone, KC | 1 |
| Moran, PM | 1 |
| Bidzan, L | 1 |
| Bidzan, M | 1 |
| Singh, S | 1 |
| Dudley, C | 1 |
| Hikida, T | 1 |
| Kitabatake, Y | 1 |
| Pastan, I | 1 |
| Nakanishi, S | 1 |
5 other studies available for donepezil and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Donepezil reverses nicotine withdrawal-induced deficits in contextual fear conditioning in C57BL/6J mice.
Topics: Animals; Cholinesterase Inhibitors; Conditioning, Psychological; Donepezil; Electroshock; Fear; Free | 2014 |
Phencyclidine withdrawal disrupts episodic-like memory in rats: reversal by donepezil but not clozapine.
Topics: Animals; Clozapine; Donepezil; Indans; Male; Memory Disorders; Memory, Episodic; Phencyclidine; Pipe | 2010 |
Withdrawal syndrome after donepezil cessation in a patient with dementia.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Delirium; Dementia; Donepezil; Female; Humans; Indans; | 2012 |
Discontinuation syndrome following donepezil cessation.
Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Dementia; Donepezil; Female; Humans; Indans; Mid | 2003 |
Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cocaine; Cocaine-Related Disorders; Conditioning, | 2003 |