donepezil has been researched along with Diabetic Neuropathies in 1 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil can activate AMPK and exerts neuroprotective effects." | 1.51 | Donepezil improves neuropathy through activation of AMPK signalling pathway in streptozotocin-induced diabetic mice. ( Ahmed, AAM; Atef, MM; El-Sayed, NM; Mostafa, YM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atef, MM | 1 |
| El-Sayed, NM | 1 |
| Ahmed, AAM | 1 |
| Mostafa, YM | 1 |
1 other study available for donepezil and Diabetic Neuropathies
| Article | Year |
|---|---|
Donepezil improves neuropathy through activation of AMPK signalling pathway in streptozotocin-induced diabetic mice.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell | 2019 |