Page last updated: 2024-10-26

donepezil and Cortical Lewy Body Disease

donepezil has been researched along with Cortical Lewy Body Disease in 69 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Research Excerpts

ExcerptRelevanceReference
"We examined attention-enhancing effects of the cholinesterase inhibitor donepezil in Dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD) by means of open label study."9.12Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with Lewy bodies. ( Burn, D; Daniel, S; McKeith, IG; Mosimann, U; Newby, J; O'Brien, JT; Rowan, E; Sanders, J; Saxby, BK; Wesnes, K, 2007)
"This open label study was designed to assess the effects of donepezil treatment, its withdrawal and subsequent recommencement on cognitive functioning, behaviour and parkinsonian symptoms in patients with probable dementia with Lewy bodies (DLB) and with Parkinson's disease who subsequently developed dementia (PDD)."9.10What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia. ( Daniel, SL; Littlewood, E; McKeith, IG; Minett, TS; Myint, P; Newby, J; Richardson, J; Sanders, J; Thomas, A; Wilkinson, LM, 2003)
" We enrolled 24 patients with DLB (diagnosed according to the Consortium on Dementia with Lewy Bodies Guideline-Revised) who experienced a relapse of BPSD despite treatment with donepezil at the standard dose (5 mg/day)."7.83Increased dosage of donepezil for the management of behavioural and psychological symptoms of dementia in dementia with Lewy bodies. ( Ino, T; Kosaka, K; Manabe, Y; Yamanaka, K, 2016)
"We reported a patient with probable dementia with Lewy bodies (DLB) showing cervical dystonia during treatment with donepezil."7.76[Case of dementia with Lewy bodies showing cervical dystonia after donepezil administration]. ( Hasegawa, N; Maeda, K; Shimada, K; Yamamoto, Y, 2010)
"She was diagnosed as having parkinsonism and took medication."5.32[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report]. ( Kondo, T; Miwa, H; Morita, S, 2004)
"We examined attention-enhancing effects of the cholinesterase inhibitor donepezil in Dementia with Lewy bodies (DLB) and Parkinson's disease with dementia (PDD) by means of open label study."5.12Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with Lewy bodies. ( Burn, D; Daniel, S; McKeith, IG; Mosimann, U; Newby, J; O'Brien, JT; Rowan, E; Sanders, J; Saxby, BK; Wesnes, K, 2007)
"This open label study was designed to assess the effects of donepezil treatment, its withdrawal and subsequent recommencement on cognitive functioning, behaviour and parkinsonian symptoms in patients with probable dementia with Lewy bodies (DLB) and with Parkinson's disease who subsequently developed dementia (PDD)."5.10What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia. ( Daniel, SL; Littlewood, E; McKeith, IG; Minett, TS; Myint, P; Newby, J; Richardson, J; Sanders, J; Thomas, A; Wilkinson, LM, 2003)
"Some randomized studies, mostly of short duration, have indicated that cholinesterase inhibitors (donepezil, rivastigmine and galantamine) may have a beneficial effect in Alzheimer's disease, vascular dementia and in dementia caused by Lewy body disease."4.84[Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?]. ( Landmark, K; Reikvam, A, 2008)
" We enrolled 24 patients with DLB (diagnosed according to the Consortium on Dementia with Lewy Bodies Guideline-Revised) who experienced a relapse of BPSD despite treatment with donepezil at the standard dose (5 mg/day)."3.83Increased dosage of donepezil for the management of behavioural and psychological symptoms of dementia in dementia with Lewy bodies. ( Ino, T; Kosaka, K; Manabe, Y; Yamanaka, K, 2016)
"We reported a patient with probable dementia with Lewy bodies (DLB) showing cervical dystonia during treatment with donepezil."3.76[Case of dementia with Lewy bodies showing cervical dystonia after donepezil administration]. ( Hasegawa, N; Maeda, K; Shimada, K; Yamamoto, Y, 2010)
"In this retrospective analysis, AD patients who had symptoms suggestive of concomitant Lewy body disease appeared to show greater treatment responses to rivastigmine than to donepezil, and experienced fewer adverse events under either drug, compared with patients without Lewy body pathology."3.73Response to rivastigmine or donepezil in Alzheimer's patients with symptoms suggestive of concomitant Lewy body pathology. ( Bergman, H; Bullock, R; Lane, R; Nagel, J; Rapatz, G; Touchon, J, 2006)
" There was no significant imbalance in the incidence of adverse events (AEs) by onset time, and delayed AE onset induced by the long-term administration of donepezil was unlikely to appear."2.78Long-term safety and efficacy of donepezil in patients with dementia with Lewy bodies: results from a 52-week, open-label, multicenter extension study. ( Hashimoto, M; Ikeda, M; Iseki, E; Kosaka, K; Matsukawa, N; Matsuo, K; Mori, E; Nakagawa, M, 2013)
"Donepezil treatment may modify regional glucose metabolism."2.75Improved visual hallucination by donepezil and occipital glucose metabolism in dementia with Lewy bodies: the Osaki-Tajiri project. ( Ishii, H; Ishikawa, H; Kasuya, M; Meguro, K; Satoh, M; Yamaguchi, S, 2010)
" An unexpectedly large placebo effect, inadequate dosage (mean 120 mg/day), and inadequate power may have contributed to lack of demonstrable benefit."2.73Quetiapine for agitation or psychosis in patients with dementia and parkinsonism. ( Cummings, J; Kurlan, R; Raman, R; Thal, L, 2007)
" Donepezil is expected to be therapeutically useful and safe in treating DLB patients, indicating marked improvements in behavioral and psychological symptoms of dementia (BPSD) rather than in cognitive deficit, without deteriorating parkinsonism."2.72Efficacy and safety of donepezil in patients with dementia with Lewy bodies: preliminary findings from an open-label study. ( Iseki, E; Kosaka, K; Mori, E; Mori, S, 2006)
"Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are the two most common types of dementing neurodegenerative disease after Alzheimer's disease (AD)."2.46Lewy body and parkinsonian dementia: common, but often misdiagnosed conditions. ( Deuschl, G; Förstl, H; Mollenhauer, B; Oertel, W; Storch, A; Trenkwalder, C, 2010)
"Studies on Alzheimer's disease and Lewy body dementias show that cholinesterase inhibitors are still first line treatment for these diseases and memantine is indicated in moderate/severe Alzheimer's disease, whereas there is as yet no standard available treatment for frontotemporal dementias."2.44Reports in pharmacological treatments in geriatric psychiatry: is there anything new or just adding to old evidence? ( Engelhardt, E; Laks, J, 2008)
"Donepezil was well tolerated, but haloperidol administration was followed by development of severe dystonia."1.43DatSCAN In Differential Diagnostics of Lewy Body Disease. ( Ivanova, K; Luzny, J, 2016)
"Lewy body disease is a common cause of dementia."1.33Successfully switching acetylcholinesterase inhibitor therapy in probable Lewy body dementia. ( Alwahhabi, FK, 2005)
"Fluctuations in consciousness and visual hallucinations are common neuropsychiatric features of dementia with Lewy bodies and Parkinson's disease dementia."1.33Change in perfusion, hallucinations and fluctuations in consciousness in dementia with Lewy bodies. ( Burn, DJ; Firbank, MJ; McKeith, IG; Mosimann, UP; O'Brien, JT, 2005)
"Delayed disease progression and symptomatic improvement occur with cholinesterase inhibitors (ChEIs) in dementia with Lewy bodies (DLB)."1.33Emergent complications following donepezil switchover to galantamine in three cases of dementia with Lewy bodies. ( Bhanji, NH; Gauthier, S, 2005)
"Treatment with donepezil and rivastigmine (successively) did not produce the desired benefits."1.32A case study in the treatment of dementia with Lewy bodies. ( Kaufer, DI, 2004)
"She was diagnosed as having parkinsonism and took medication."1.32[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report]. ( Kondo, T; Miwa, H; Morita, S, 2004)
"Donepezil therapy was discontinued prematurely in three of the cases due to insufficient response and/or adverse events."1.31Donepezil for behavioural disorders associated with Lewy bodies: a case series. ( Herrmann, N; Lanctôt, KL, 2000)
"Bromperidol 12 mg was prescribed to treat his symptoms."1.31[Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies]. ( Iwado, H; Morita, Y; Shinjo, H; Ueki, A, 2001)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's43 (62.32)29.6817
2010's26 (37.68)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikeda, M8
Mori, E7
Kosaka, K11
Iseki, E5
Hashimoto, M2
Matsukawa, N1
Matsuo, K2
Nakagawa, M6
Leikin, JB1
Braund, V1
DesLauris, C1
Shoji, M1
Tagawa, R1
Hashimoto, H1
Nakanishi, A1
Kawarada, Y1
Muramatsu, T1
Matsuda, Y1
Kataoka, K1
Shimada, A1
Uchida, K1
Yoshida, A1
Higashiyama, S1
Kawabe, J1
Kai, T2
Shiomi, S1
Mori, H1
Inoue, K1
Manabe, Y1
Ino, T1
Yamanaka, K1
Miyagishi, H4
Yamaguchi, H1
Szigeti, K1
Hafeez, MU1
Katayama, S1
Higashi, Y1
Cummings, J2
Lai, TJ1
Hemrungrojn, S1
Mohandas, E1
Yun Kim, S1
Nair, G1
Dash, A1
Nakai, K1
Luzny, J1
Ivanova, K1
Kazui, H1
Adachi, H1
Kanemoto, H1
Yoshiyama, K1
Wada, T1
Tokumasu Nomura, K1
Tanaka, T1
Josif, S1
Graham, K1
Laks, J1
Engelhardt, E1
Kurota, S1
Hasegawa, N1
Shimada, K1
Yamamoto, Y1
Maeda, K2
Fujita, Y1
Takebayashi, M1
Kinoshita, T1
Hanabusa, H1
Mollenhauer, B1
Förstl, H1
Deuschl, G1
Storch, A1
Oertel, W1
Trenkwalder, C1
Satoh, M1
Ishikawa, H1
Meguro, K1
Kasuya, M1
Ishii, H1
Yamaguchi, S1
Ukai, K1
Nakamura, R1
Sobue, G1
Shibayama, H1
Iritani, S1
Ishihara, R1
Ozaki, N1
Landau, R1
Shinfuku, M1
Nakajima, S1
Uchida, H1
Watanabe, K1
Kocha, H1
Kashima, H1
Rolinski, M1
Fox, C1
Maidment, I1
McShane, R1
Lindberg, OM1
Hayashi, H1
Kawakatsu, S1
Suzuki, A1
Shibuya, Y1
Kobayashi, R1
Sato, C1
Otani, K1
Ozaki, A1
Nishida, M1
Koyama, K1
Ishikawa, K1
Nishikawa, T1
Minett, TS1
Thomas, A3
Wilkinson, LM1
Daniel, SL1
Sanders, J3
Richardson, J2
Littlewood, E2
Myint, P1
Newby, J3
McKeith, IG6
Onofrj, M1
Kaufer, DI2
Terao, T2
Shimomura, T1
Izumi, Y1
Nakamura, J1
Matsumoto, T1
Kawanishi, C1
Isojima, D1
Kishida, I1
Massironi, G1
Galluzzi, S1
Frisoni, GB1
Rozzini, L1
Ghianda, D1
Trabucchi, M1
Padovani, A1
Morita, S1
Miwa, H1
Kondo, T1
Simard, M1
van Reekum, R1
Alwahhabi, FK1
O'Brien, JT4
Firbank, MJ1
Mosimann, UP2
Burn, DJ3
Asai, Y1
Sakuma, K1
Koeda, T1
Nakashima, K1
Thomas, AJ1
Rowan, EN1
Cousins, D1
Pakrasi, S2
Bhanji, NH1
Gauthier, S1
Touchon, J1
Bergman, H1
Bullock, R1
Rapatz, G1
Nagel, J1
Lane, R1
Mori, T1
Fukuhara, R1
Nestor, PJ1
Tanabe, H1
Mori, S1
Ringman, JM1
Cummings, JL1
Cousins, DA1
Lett, D1
Johannsen, P1
Rowan, E2
Saxby, BK1
Burn, D1
Mosimann, U1
Daniel, S1
Wesnes, K1
Bhasin, M1
Edwards, K1
McKeith, I1
Kurlan, R1
Raman, R1
Thal, L1
Omerovic, M1
Teipel, SJ1
Hampel, T1
Ballard, CG1
Chalmers, KA1
Todd, C1
Wilcock, G1
Love, S1
Perry, EK1
Anghelescu, I1
Heuser, I1
Landmark, K1
Reikvam, A1
Fergusson, E1
Howard, R1
Lanctôt, KL1
Herrmann, N1
Collinson, S1
Samuel, W1
Caligiuri, M1
Galasko, D1
Lacro, J1
Marini, M1
McClure, FS1
Warren, K1
Jeste, DV1
Skjerve, A1
Nygaard, HA1
Rojas-Fernandez, CH1
Ueki, A1
Iwado, H1
Shinjo, H1
Morita, Y1
Arahata, H1
Ohyagi, Y1
Matsumoto, S1
Furuya, H1
Murai, H1
Kuwabara, Y1
Yamada, T1
Kira, J1
Coulson, BS1
Fenner, SG1
Almeida, OP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-targets, Single-lead GPi+NBM DBS in Parkinson's Disease With Mild Cognitive Impairment[NCT04571112]6 participants (Actual)Interventional2017-12-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for donepezil and Cortical Lewy Body Disease

ArticleYear
[Programs for continuing medical education: a session; 3. Dementia: diagnosis and therapy].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Mar-10, Volume: 103, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cholinesterase Inhibitors; Cognitive Dysfuncti

2014
Exploring the role of donepezil in dementia with Lewy bodies.
    Drugs of today (Barcelona, Spain : 1998), 2015, Volume: 51, Issue:10

    Topics: Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Humans; Indans; Lewy Body Disease; P

2015
Role of Donepezil in the Management of Neuropsychiatric Symptoms in Alzheimer's Disease and Dementia with Lewy Bodies.
    CNS neuroscience & therapeutics, 2016, Volume: 22, Issue:3

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Lewy Body Disease; Piperidi

2016
Diagnosis and treatment of dementia with Lewy bodies.
    JAAPA : official journal of the American Academy of Physician Assistants, 2008, Volume: 21, Issue:5

    Topics: Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Lewy Body Disease; Nootropic Agen

2008
Reports in pharmacological treatments in geriatric psychiatry: is there anything new or just adding to old evidence?
    Current opinion in psychiatry, 2008, Volume: 21, Issue:6

    Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Donepezil; Drug Therapy; Evidence-Base

2008
[Clinical and pathological findings in dementia with Lewy bodies].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2008, Volume: 110, Issue:7

    Topics: Aged; Atrophy; Brain; Cholinesterase Inhibitors; Diagnosis, Differential; Diagnostic Imaging; Donepe

2008
Issues facing home-based medical support services.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2010, Volume: 10, Issue:2

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Caregivers; Delirium; Dementia; Diagnosis, Differenti

2010
Lewy body and parkinsonian dementia: common, but often misdiagnosed conditions.
    Deutsches Arzteblatt international, 2010, Volume: 107, Issue:39

    Topics: Aged; Brain; Cholinesterase Inhibitors; Cross-Sectional Studies; Dementia; Diagnosis, Differential;

2010
Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease.
    The Cochrane database of systematic reviews, 2012, Mar-14, Issue:3

    Topics: Cholinesterase Inhibitors; Cognition Disorders; Dementia; Donepezil; Humans; Indans; Lewy Body Disea

2012
[Diffuse Lewy body disease].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003, Aug-10, Volume: 92, Issue:8

    Topics: Cholinesterase Inhibitors; Donepezil; History, 20th Century; Humans; Indans; Lewy Body Disease; Pipe

2003
[Dementia with Lewy bodies].
    Ryoikibetsu shokogun shirizu, 2003, Issue:40

    Topics: Aged; Antipsychotic Agents; Brain; Cholinesterase Inhibitors; Diagnostic Imaging; Donepezil; Dopamin

2003
The acetylcholinesterase inhibitors for treatment of cognitive and behavioral symptoms in dementia with Lewy bodies.
    The Journal of neuropsychiatry and clinical neurosciences, 2004,Fall, Volume: 16, Issue:4

    Topics: Aged; Basal Ganglia Diseases; Behavior; Cholinesterase Inhibitors; Clinical Trials as Topic; Cogniti

2004
[Community strategies for rehabilitation in senile dementia].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2005, Volume: 107, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Community Mental Health Services; Diagnosis, Differentia

2005
Current and emerging pharmacological treatment options for dementia.
    Behavioural neurology, 2006, Volume: 17, Issue:1

    Topics: Acetylcholine; Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Donepezil; Galantamine; Human

2006
[Medical treatment of Alzheimer's disease].
    Ugeskrift for laeger, 2006, Oct-02, Volume: 168, Issue:40

    Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic;

2006
[Acetylcholinesterase inhibitors for dementia--an update].
    MMW Fortschritte der Medizin, 2007, May-21, Volume: 149 Suppl 2

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dementia; Donepezil; Galanta

2007
[Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2008, Jan-31, Volume: 128, Issue:3

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Dementia, Vascular; Donepezil; Evidence-Base

2008
Successful treatment of behavioural problems in dementia using a cholinesterase inhibitor: the ethical questions.
    The Australian and New Zealand journal of psychiatry, 2002, Volume: 36, Issue:2

    Topics: Aged; Aged, 80 and over; Australia; Cholinesterase Inhibitors; Donepezil; Ethics; Hallucinations; Hu

2002

Trials

13 trials available for donepezil and Cortical Lewy Body Disease

ArticleYear
Long-term safety and efficacy of donepezil in patients with dementia with Lewy bodies: results from a 52-week, open-label, multicenter extension study.
    Dementia and geriatric cognitive disorders, 2013, Volume: 36, Issue:3-4

    Topics: Aged; Aged, 80 and over; Data Interpretation, Statistical; Disease Progression; Donepezil; Double-Bl

2013
Effects of Donepezil on Extrapyramidal Symptoms in Patients with Dementia with Lewy Bodies: A Secondary Pooled Analysis of Two Randomized-Controlled and Two Open-Label Long-Term Extension Studies.
    Dementia and geriatric cognitive disorders, 2015, Volume: 40, Issue:3-4

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Datasets as Topic; Disease Progression; Donepezi

2015
Adequacy of Using Consensus Guidelines for Diagnosis of Dementia with Lewy Bodies in Clinical Trials for Drug Development.
    Dementia and geriatric cognitive disorders, 2016, Volume: 41, Issue:1-2

    Topics: Aged; Aged, 80 and over; Consensus; Dementia; Donepezil; Female; Guideline Adherence; Humans; Indans

2016
Increased plasma donepezil concentration improves cognitive function in patients with dementia with Lewy bodies: An exploratory pharmacokinetic/pharmacodynamic analysis in a phase 3 randomized controlled trial.
    Journal of the neurological sciences, 2016, Jul-15, Volume: 366

    Topics: Aged; Aged, 80 and over; Blood Pressure; Body Weight; Cognition; Cytochrome P-450 CYP2D6; Donepezil;

2016
Pretreatment Cognitive Profile Likely to Benefit from Donepezil Treatment in Dementia with Lewy Bodies: Pooled Analyses of Two Randomized Controlled Trials.
    Dementia and geriatric cognitive disorders, 2016, Volume: 42, Issue:1-2

    Topics: Aged; Cognition; Donepezil; Drug Monitoring; Female; Humans; Indans; Lewy Body Disease; Male; Mental

2016
Improved visual hallucination by donepezil and occipital glucose metabolism in dementia with Lewy bodies: the Osaki-Tajiri project.
    European neurology, 2010, Volume: 64, Issue:6

    Topics: Aged, 80 and over; Donepezil; Female; Glucose; Hallucinations; Humans; Image Interpretation, Compute

2010
Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled trial.
    Annals of neurology, 2012, Volume: 72, Issue:1

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Cognition; Donepezil; Double-Blind Method; Femal

2012
What happens when donepezil is suddenly withdrawn? An open label trial in dementia with Lewy bodies and Parkinson's disease with dementia.
    International journal of geriatric psychiatry, 2003, Volume: 18, Issue:11

    Topics: Cholinesterase Inhibitors; Dementia; Donepezil; Drug Administration Schedule; Humans; Indans; Lewy B

2003
Efficacy and safety of donepezil in patients with dementia with Lewy bodies: preliminary findings from an open-label study.
    Psychiatry and clinical neurosciences, 2006, Volume: 60, Issue:2

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Donepezil; Feasibility Studies; Female; Humans;

2006
Cholinesterase inhibitors in advanced Dementia with Lewy bodies: increase or stop?
    International journal of geriatric psychiatry, 2006, Volume: 21, Issue:8

    Topics: Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Humans; Indans; Lewy Body Di

2006
Effects of donepezil on central processing speed and attentional measures in Parkinson's disease with dementia and dementia with Lewy bodies.
    Dementia and geriatric cognitive disorders, 2007, Volume: 23, Issue:3

    Topics: Aged; Aged, 80 and over; Attention; Chi-Square Distribution; Cholinesterase Inhibitors; Cognition; D

2007
Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
    Neurology, 2007, Apr-24, Volume: 68, Issue:17

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Antiparkinson Agents; Antips

2007
Better cognitive and psychopathologic response to donepezil in patients prospectively diagnosed as dementia with Lewy bodies: a preliminary study.
    International journal of geriatric psychiatry, 2000, Volume: 15, Issue:9

    Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Electromyography

2000

Other Studies

38 other studies available for donepezil and Cortical Lewy Body Disease

ArticleYear
Cholinergic symptoms with low serum cholinesterase from therapeutic cholinesterase inhibitor toxicity.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:7

    Topics: Aged; Bradycardia; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Humans; Indans; Lewy Body

2014
The Relationship Between Medial Temporal Lobe Atrophy and Cognitive Impairment in Patients With Dementia With Lewy Bodies.
    Journal of geriatric psychiatry and neurology, 2015, Volume: 28, Issue:4

    Topics: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Atrophy; Cognition Disorders; Do

2015
Increased dosage of donepezil for the management of behavioural and psychological symptoms of dementia in dementia with Lewy bodies.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016, Volume: 16, Issue:3

    Topics: Aged; Aged, 80 and over; Behavior; Behavioral Symptoms; Cholinesterase Inhibitors; Cognition; Dement

2016
DatSCAN In Differential Diagnostics of Lewy Body Disease.
    Archives of Iranian medicine, 2016, Volume: 19, Issue:6

    Topics: Aged, 80 and over; Alzheimer Disease; Czech Republic; Diagnosis, Differential; Donepezil; Female; Hu

2016
Effects of donepezil on sleep disturbances in patients with dementia with Lewy bodies: An open-label study with actigraphy.
    Psychiatry research, 2017, Volume: 251

    Topics: Actigraphy; Aged; Aged, 80 and over; Delusions; Donepezil; Dose-Response Relationship, Drug; Drug Ad

2017
[Case of dementia with Lewy bodies showing cervical dystonia after donepezil administration].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:3

    Topics: Aged; Donepezil; Electromyography; Female; Humans; Indans; Lewy Body Disease; Piperidines; Torticoll

2010
Efficacy of low-dose donepezil for visual hallucinations in a patient with dementia with Lewy bodies.
    Psychiatry and clinical neurosciences, 2010, Volume: 64, Issue:3

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Female; Hallucinations

2010
A case of dementia with Lewy bodies that temporarily showed symptoms similar to Creutzfeldt-Jakob disease.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2010, Volume: 10, Issue:4

    Topics: Aged; Brain Ischemia; Cholinesterase Inhibitors; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential

2010
Lewy body and parkinsonian dementia: common, but often misdiagnosed conditions: Evidence is not satisfactory.
    Deutsches Arzteblatt international, 2011, Volume: 108, Issue:8

    Topics: Aged; Brain; Cholinesterase Inhibitors; Cross-Sectional Studies; Dementia; Diagnosis, Differential;

2011
Pisa syndrome caused by an acetylcholinesterase inhibitor in a patient with dementia with Lewy bodies.
    Psychiatry and clinical neurosciences, 2011, Volume: 65, Issue:3

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Dyskinesia, Drug-Induced; Female; Humans; Indans; Lewy B

2011
[Why choose another cholinesterase inhibitor than donepezil?].
    Ugeskrift for laeger, 2012, Sep-24, Volume: 174, Issue:39

    Topics: Cholinesterase Inhibitors; Conflict of Interest; Donepezil; Drug Costs; Humans; Indans; Lewy Body Di

2012
Application of the VSRAD, a specific and sensitive voxel-based morphometry, to comparison of entorhinal cortex atrophy between dementia with Lewy bodies and Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2012, Volume: 34, Issue:5-6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atrophy; Data Interpretation, Statistical; Donepezil; En

2012
Donepezil-induced sleep spindle in a patient with dementia with Lewy bodies: a case report.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2012, Volume: 12, Issue:4

    Topics: Aged, 80 and over; Cholinesterase Inhibitors; Cognition; Donepezil; Female; Humans; Indans; Lewy Bod

2012
Severe worsening of parkinsonism in Lewy body dementia due to donepezil.
    Neurology, 2003, Nov-25, Volume: 61, Issue:10

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Disease; Piperidines

2003
Pharmacologic treatment expectations in the management of dementia with Lewy bodies.
    Dementia and geriatric cognitive disorders, 2004, Volume: 17 Suppl 1

    Topics: Aged; Alzheimer Disease; Antipsychotic Agents; Brain; Carbamates; Cholinesterase Inhibitors; Diagnos

2004
Two cases of quetiapine augmentation for donepezil-refractory visual hallucinations in dementia with Lewy bodies.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:12

    Topics: Aged; Antipsychotic Agents; Dibenzothiazepines; Donepezil; Drug Resistance; Drug Synergism; Drug The

2003
Neuroleptic malignant syndrome induced by donepezil.
    The international journal of neuropsychopharmacology, 2004, Volume: 7, Issue:1

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Disease; Neuroleptic M

2004
Drug treatment of REM sleep behavior disorders in dementia with Lewy bodies.
    International psychogeriatrics, 2003, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Ambulatory Care; Benzodiazepines; Cholinesterase Inhibitors; Clonazepam; Do

2003
A case study in the treatment of dementia with Lewy bodies.
    Acta psychiatrica Scandinavica, 2004, Volume: 110, Issue:1

    Topics: Aged; Aged, 80 and over; Carbamates; Cognition Disorders; Donepezil; Drug Resistance; Female; Galant

2004
Severe worsening of parkinsonism in Lewy body dementia due to donepezil.
    Neurology, 2004, Oct-26, Volume: 63, Issue:8

    Topics: Acetylcholine; Aged; Basal Ganglia; Cholinesterase Inhibitors; Disease Progression; Donepezil; Dopam

2004
[A patient with probable dementia with Lewy bodies, who showed catatonia induced by donepezil: a case report].
    No to shinkei = Brain and nerve, 2004, Volume: 56, Issue:10

    Topics: Aged; Catatonia; Donepezil; Female; Hallucinations; Humans; Indans; Lewy Body Disease; Nootropic Age

2004
Successfully switching acetylcholinesterase inhibitor therapy in probable Lewy body dementia.
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:2

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Disease; Neuroprotecti

2005
Change in perfusion, hallucinations and fluctuations in consciousness in dementia with Lewy bodies.
    Psychiatry research, 2005, Jul-30, Volume: 139, Issue:2

    Topics: Aged; Cholinesterase Inhibitors; Consciousness Disorders; Donepezil; Female; Hallucinations; Hemodyn

2005
Quantitative electroencephalogram analysis in dementia with Lewy bodies and Alzheimer's disease.
    Journal of the neurological sciences, 2005, Oct-15, Volume: 237, Issue:1-2

    Topics: Aged; Algorithms; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Electroencephalography; F

2005
A comparison of the efficacy of donepezil in Parkinson's disease with dementia and dementia with Lewy bodies.
    International journal of geriatric psychiatry, 2005, Volume: 20, Issue:10

    Topics: Age Factors; Aged; Cholinesterase Inhibitors; Dementia; Donepezil; Female; Humans; Indans; Lewy Body

2005
Emergent complications following donepezil switchover to galantamine in three cases of dementia with Lewy bodies.
    The Journal of neuropsychiatry and clinical neurosciences, 2005,Fall, Volume: 17, Issue:4

    Topics: Aged; Cholinesterase Inhibitors; Disease Progression; Donepezil; Galantamine; Humans; Indans; Lewy B

2005
Response to rivastigmine or donepezil in Alzheimer's patients with symptoms suggestive of concomitant Lewy body pathology.
    Current medical research and opinion, 2006, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Double-Blind Metho

2006
Correlation of visual hallucinations with occipital rCBF changes by donepezil in DLB.
    Neurology, 2006, Mar-28, Volume: 66, Issue:6

    Topics: Aged; Aged, 80 and over; Cerebrovascular Circulation; Donepezil; Female; Hallucinations; Humans; Ind

2006
Cholinesterase inhibitors in dementia with Lewy bodies: a comparative analysis.
    International journal of geriatric psychiatry, 2007, Volume: 22, Issue:9

    Topics: Aged; Analysis of Variance; Cholinesterase Inhibitors; Clinical Trials as Topic; Data Interpretation

2007
[Dementia with Lewy bodies. Clinical improvement under treatment with an acetylcholinesterase inhibitor].
    Der Nervenarzt, 2007, Volume: 78, Issue:9

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Hallucinations; Humans; Indans; Lewy Body Disease; Male;

2007
Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.
    Neurology, 2007, May-15, Volume: 68, Issue:20

    Topics: Aged; Aged, 80 and over; Amyloid beta-Peptides; Autopsy; Cerebral Cortex; Cholinesterase Inhibitors;

2007
Donepezil for the treatment of psychosis in dementia with Lewy bodies.
    International journal of geriatric psychiatry, 2000, Volume: 15, Issue:3

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Disease; Male; Piperid

2000
Donepezil for behavioural disorders associated with Lewy bodies: a case series.
    International journal of geriatric psychiatry, 2000, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Dis

2000
Charles Bonnet syndrome and dementia.
    Lancet (London, England), 2000, Jun-17, Volume: 355, Issue:9221

    Topics: Aged; Diagnosis, Differential; Donepezil; Female; Hallucinations; Humans; Indans; Lewy Body Disease;

2000
Improvement in sundowning in dementia with Lewy bodies after treatment with donepezil.
    International journal of geriatric psychiatry, 2000, Volume: 15, Issue:12

    Topics: Aged; Cholinesterase Inhibitors; Circadian Rhythm; Donepezil; Humans; Indans; Lewy Body Disease; Mal

2000
Successful use of donepezil for the treatment of dementia with Lewy bodies.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:2

    Topics: Aged; Aged, 80 and over; Cholinesterase Inhibitors; Donepezil; Female; Humans; Indans; Lewy Body Dis

2001
[Malignant syndrome caused by a combination of bromperidol and donepezil hydrochloride in a patient with probable dementia with Lewy bodies].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:6

    Topics: Aged; Donepezil; Drug Therapy, Combination; Hallucinations; Haloperidol; Humans; Indans; Lewy Body D

2001
[A patient with probable dementia with Lewy bodies, who showed improvement of dementia and parkinsonism by the administratim of donepezil].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:7

    Topics: Aged; Cholinesterase Inhibitors; Donepezil; Electroencephalography; Humans; Indans; Lewy Body Diseas

2001