donepezil has been researched along with Colonic Inertia in 2 studies
Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.
Colonic Inertia: Symptom characterized by the passage of stool once a week or less.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(1) Donepezil can reduce memory loss, dry mouth, and constipation in nongeriatric affective patients, but may trigger mania; and (2) long-term follow-up will reveal the predictive value for dementia of donepezil's memory restoration in nongeriatric subjects." | 5.09 | Donepezil for psychotropic-induced memory loss. ( Comas-Díaz, L; Jacobsen, FM, 1999) |
| "Donepezil is a high-affinity ligand for acetylcholinesterase-the enzyme that catabolizes acetylcholine in cholinergic synapses." | 1.42 | Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET. ( Borghammer, P; Brooks, DJ; Danielsen, EH; Fedorova, T; Gjerløff, T; Hansen, J; Jacobsen, S; Knudsen, K; Munk, OL; Nahimi, A; Pavese, N; Terkelsen, AJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gjerløff, T | 1 |
| Fedorova, T | 1 |
| Knudsen, K | 1 |
| Munk, OL | 1 |
| Nahimi, A | 1 |
| Jacobsen, S | 1 |
| Danielsen, EH | 1 |
| Terkelsen, AJ | 1 |
| Hansen, J | 1 |
| Pavese, N | 1 |
| Brooks, DJ | 1 |
| Borghammer, P | 1 |
| Jacobsen, FM | 1 |
| Comas-Díaz, L | 1 |
1 trial available for donepezil and Colonic Inertia
| Article | Year |
|---|---|
Donepezil for psychotropic-induced memory loss.
Topics: Adult; Ambulatory Care; Cholinesterase Inhibitors; Constipation; Depressive Disorder; Diarrhea; Dizz | 1999 |
1 other study available for donepezil and Colonic Inertia
| Article | Year |
|---|---|
Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET.
Topics: Acetylcholinesterase; Adult; Aged; Antiparkinson Agents; Brain; Case-Control Studies; Cholinesterase | 2015 |