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donepezil and Cirrhosis, Liver

donepezil has been researched along with Cirrhosis, Liver in 1 studies

Donepezil: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
donepezil : A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one : A member of the class of indanones that is 5,6-dimethoxyindan-1-one which is substituted at position 2 by an (N-benzylpiperidin-4-yl)methyl group.

Research Excerpts

ExcerptRelevanceReference
"Donepezil was equally well tolerated by all subjects."2.69An evaluation of the pharmacokinetics of donepezil HCl in patients with impaired hepatic function. ( Friedhoff, LT; Perdomo, CA; Tiseo, PJ; Vargas, R, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tiseo, PJ1
Vargas, R1
Perdomo, CA1
Friedhoff, LT1

Trials

1 trial available for donepezil and Cirrhosis, Liver

ArticleYear
An evaluation of the pharmacokinetics of donepezil HCl in patients with impaired hepatic function.
    British journal of clinical pharmacology, 1998, Volume: 46 Suppl 1

    Topics: Administration, Oral; Adult; Aged; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid;

1998